X0306 4 2016-01-04 0 0001339970 aTYR PHARMA INC LIFE 0001662549 Ravindran Sanuj K. 3545 JOHN HOPKINS COURT, SUITE 250 SAN DIEGO CA 92121 0 1 0 0 Chief Business Officer Employee Stock Option (right to buy) 9.13 2016-01-04 4 A 0 153000 0.00 A 2026-01-04 Common Stock 153000 153000 D Employee Stock Option (right to buy) 9.13 2016-01-04 4 A 0 10750 0.00 A Common Stock 10750 10750 D 1/4th of the shares subject to this option shall vest and become exercisable on January 4, 2017 and the remaining shares subject to this option shall vest and become exercisable in 36 equal monthly installments, such that this option is fully exercisable on January 4, 2020. This option is subject to accelerated vesting upon termination without cause upon a change of control of the Issuer. The shares subject to this option shall vest and become exercisable, if at all, in 48 equal monthly installments upon the achievement of certain performance goals, which must be achieved by January 4, 2018, or such option will be subject to immediate forfeiture. This option is subject to accelerated vesting upon termination without cause upon a change of control of the issuer. /s/ Nancy Krueger, as Power of Attorney 2016-01-06