Stock-Based Compensation - Stock-Based Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019	Jun. 30, 2020	Jun. 30, 2019
Stock-Based Compensation [Abstract]
Stock-based compensation expense	$ 16,121	$ 14,363	$ 23,402	$ 32,923
Cost of Sales - Product [Member]
Stock-Based Compensation [Abstract]
Stock-based compensation expense	350	137	587	255
Research and Development Expenses [Member]
Stock-Based Compensation [Abstract]
Stock-based compensation expense	3,484	2,563	4,833	6,484
Selling, General and Administrative Expenses [Member]
Stock-Based Compensation [Abstract]
Stock-based compensation expense	$ 12,287	$ 11,663	$ 17,982	$ 26,184