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Clinical material acquired.

No definition available.

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Value of commercial inotersen inventory held by Ionis, which will be paid in cash and recorded as a reduction of additional paid in capital.

No definition available.

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TTR Development, Commercialization, Collaboration and License Agreement [Abstract]

No definition available.

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Liability for costs incurred and expensed by Ionis Pharmaceuticals, Inc. prior to the closing of the TTR license agreement.

No definition available.

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The maximum amount of payments payable for milestones under the collaboration agreement.

No definition available.

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The period of time required for the Company to provide written notice requesting termination of the License Agreement with Ionis Pharmaceuticals, Inc. (Ionis), in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

No definition available.

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The number of sales milestones under the agreement.

No definition available.

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The percentage of profits and losses from the development and commercialization of inotersen paid to Ionis through the end of the quarter in which the first commercial sale of AKCEA-TTR-LRx occurs.

No definition available.

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The percentage of profits and losses from the development and commercialization of inotersen paid to Ionis on the first day of the first quarter after the first commercial sale of AKCEA-TTR-LRx occurs.

No definition available.

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The percentage of profits and losses from the development and commercialization of inotersen retained by the Company through the end of the quarter in which the first commercial sale of AKCEA-TTR-LRx occurs.

No definition available.

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The percentage of profits and losses from the development and commercialization of inotersen retained by the Company on the first day of the first quarter after the first commercial sale of AKCEA-TTR-LRx occurs.

No definition available.

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The percentage of profits and losses from the development and commercialization of AKCEA-TTR-L paid to Ionis.

No definition available.

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The percentage of profits and losses from the development and commercialization of AKCEA-TTR-L retained by the Company.

No definition available.

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The number of shares issued for the upfront licensing of TEGSEDI (inotersen) and AKCEA-TTR-L.

No definition available.

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The upfront licensing fee paid for the grant of rights under the License Agreement with Ionis Pharmaceuticals, Inc. (Ionis).

No definition available.

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Value of common stock issued to pay for regulatory milestone.

No definition available.

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The maximum number of common shares permitted to be issued by an entity's charter and bylaws.

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Amount of expense for allocation of cost of intangible asset over its useful life directly used in production of good and rendering of service.

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Useful life of finite-lived intangible assets, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Amount after amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.

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The cash inflow from the additional capital contribution to the entity.

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Number of new stock issued during the period.

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