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Significant Accounting Policies, Research and Development Expenses (Details) - Novartis [Member] - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Mar. 31, 2017
Jun. 30, 2017
Research and Development Expenses [Abstract]    
Sublicense fee expenses $ 48.4  
Non-cash sublicense expenses 33.4  
Allocable arrangement consideration   $ 108.4
Portion of upfront payment paid as sublicense fee to Ionis 15.0  
Upfront payment received 75.0  
Premium received on shares issued by Ionis 28.4  
Premium received if IPO is not completed $ 5.0 $ 5.0
Number of months from inception of agreement for IPO to be completed   15 months
Percentage of license fees, milestone payments and royalties paid as sublicense fee to Ionis   50.00%