CONDENSED CONSOLIDATED BALANCE SHEETS (Unaudited) - USD ($) $ in Thousands	Jun. 30, 2017	Dec. 31, 2016
Current assets:
Cash and cash equivalents	$ 75,445	$ 7,857
Short-term investments	43,223	0
Other current assets	3,939	1,209
Total current assets	122,607	9,066
Property, plant and equipment, net	114	177
Licenses, net	1,281	1,341
Deposits and other assets	102	100
Total assets	124,104	10,684
Current liabilities:
Accounts payable	143	476
Payable to Ionis Pharmaceuticals, Inc.	11,244	24,355
Accrued compensation	1,252	2,505
Accrued liabilities	2,213	1,041
Current portion of deferred revenue	54,155	0
Current portion of deferred rent	40	33
Total current liabilities	69,047	28,410
Long-term portion of deferred rent	18	21
Line of credit with Ionis Pharmaceuticals, Inc.	107,507	0
Long-term portion of deferred revenue	30,515	0
Total liabilities	207,087	28,431
Stockholders' equity (deficit):
Series A convertible preferred stock, $0.001 par value; 28,884,540 shares authorized, issued and outstanding at June 30, 2017 and December 31, 2016, respectively; aggregate liquidation value of $628,613 and $610,304 as of June 30, 2017 and December 31, 2016, respectively; no shares authorized, issued or outstanding	100,000	100,000
Common stock, $0.001 par value; 100,000,000 shares authorized and 0 shares issued and outstanding at June 30, 2017 and December 31, 2016, respectively	0	0
Additional paid-in capital	64,059	56,936
Accumulated other comprehensive loss	(84)	(21)
Accumulated deficit	(246,958)	(174,662)
Total stockholders' equity (deficit)	(82,983)	(17,747)
Total liabilities and stockholders' equity (deficit)	$ 124,104	$ 10,684