<SEC-DOCUMENT>0000912057-17-000029-index.html : 20170327
<SEC-HEADER>0000912057-17-000029.hdr.sgml : 20170327
<ACCEPTANCE-DATETIME>20170210210146
<PRIVATE-TO-PUBLIC>
ACCESSION NUMBER:		0000912057-17-000029
CONFORMED SUBMISSION TYPE:	DRS/A
PUBLIC DOCUMENT COUNT:		7
FILED AS OF DATE:		20170213
<PUBLIC-REL-DATE>20170327
DATE AS OF CHANGE:		20170223

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AKCEA THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001662524
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				472608175
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DRS/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	377-01321
		FILM NUMBER:		17595488

	BUSINESS ADDRESS:	
		STREET 1:		55 CAMBRIDGE PARKWAY
		STREET 2:		SUITE 100
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
		BUSINESS PHONE:		760-603-2732

	MAIL ADDRESS:	
		STREET 1:		2855 GAZELLE CT
		CITY:			CARLSBAD
		STATE:			CA
		ZIP:			92010
</SEC-HEADER>
<DOCUMENT>
<TYPE>DRS/A
<SEQUENCE>1
<FILENAME>filename1.htm
<TEXT>
Document 1 - file: filename1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.4
<SEQUENCE>2
<FILENAME>filename2.htm
<TEXT>
Document 2 - file: filename2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.5
<SEQUENCE>3
<FILENAME>filename3.htm
<TEXT>
Document 3 - file: filename3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.7
<SEQUENCE>4
<FILENAME>filename4.htm
<TEXT>
Document 4 - file: filename4.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.8
<SEQUENCE>5
<FILENAME>filename5.htm
<TEXT>
Document 5 - file: filename5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.15
<SEQUENCE>6
<FILENAME>filename6.htm
<TEXT>
Document 6 - file: filename6.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>g103162kk01i001.gif
<TEXT>
Document 7 - file: g103162kk01i001.gif

</DOCUMENT>
</SEC-DOCUMENT>