144 0001662521 XXXXXXXX LIVE 0001159036 HALOZYME THERAPEUTICS, INC. 001-32335 12390 El Camino Real San Diego CA 92130 8587948889 BERNADETTE CONNAUGHTON Director Common Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza 8th Floor New York NY 10004

2000 140620.00 117597000 01/05/2026 NASDAQ Common 05/05/2022 Restricted Stock Units Issuer N 2000 05/05/2022 N/A N 10b5-1 Sales for BERNADETTE CONNAUGHTON

12390 El Camino Real San Diego CA 92130

Common 12/01/2025 829 59356.40 10b5-1 Sales for BERNADETTE CONNAUGHTON

12390 El Camino Real San Diego CA 92130

Common 11/10/2025 2000 136960.00 01/05/2026 05/29/2025 /s/ Bernadette Mary Connaughton