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Stock Incentive Plans - Summary of Option Activity under Plans (Details)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2020
USD ($)
$ / shares
shares
Dec. 31, 2019
USD ($)
$ / shares
shares
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]    
Number of Options, Outstanding at Beginning Balance | shares 4,843,018  
Number of Options, Granted | shares 1,200,650  
Number of Options, Exercised | shares (41,593)  
Number of Options, Cancelled/Forfeited | shares (189,243)  
Number of Options, Outstanding at Ending Balance | shares 5,812,832 4,843,018
Number of Options, Vested and Expected to vest at March 31, 2020 | shares 5,812,832  
Number of Options, Exercisable at March 31, 2020 | shares 2,574,662  
Weighted-Average Exercise Price per Share, Outstanding at Beginning Balance | $ / shares $ 14.78  
Weighted-Average Exercise Price per Share, Granted | $ / shares 18.43  
Weighted-Average Exercise Price per Share, Exercised | $ / shares 3.84  
Weighted-Average Exercise Price per Share, Cancelled/Forfeited | $ / shares 23.31  
Weighted-Average Exercise Price per Share, Outstanding at Ending Balance | $ / shares 15.33 $ 14.78
Weighted-Average Exercise Price per Share, Vested and Expected to vest at March 31, 2020 | $ / shares 15.33  
Weighted-Average Exercise Price Per Share, Exercisable at March 31, 2020 | $ / shares $ 11.70  
Weighted Average Remaining Contractual Term, Outstanding 8 years 1 month 6 days 8 years 6 months
Weighted Average Remaining Contractual Term, Vested and Expected to vest at March 31, 2020 8 years 1 month 6 days  
Weighted Average Remaining Contractual Term, Exercisable at March 31, 2020 7 years 3 months 18 days  
Aggregate Intrinsic Value, Outstanding Ending Balance | $ $ 11,299 $ 33,809
Aggregate Intrinsic Value, Vested and Expected to vest at March 31, 2020 | $ 11,299  
Aggregate Intrinsic Value, Exercisable at March 31, 2020 | $ $ 9,618