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Income Taxes - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 22, 2017
Dec. 31, 2018
Dec. 31, 2017
Income Tax Disclosure [Line Items]      
U.S. corporate tax rate 21.00% 21.00% 34.00%
Income tax expense   $ 0 $ 0
Increase in valuation allowance due to deferred tax assets   25,100,000 7,700,000
Uncertain tax positions   0  
Income tax expense, interest or penalties   0 $ 0
Orphan Drug      
Income Tax Disclosure [Line Items]      
Tax credit carryforwards   $ 7,300,000  
Tax credit carryforwards expiration year   2038  
Federal      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards   $ 52,400,000  
Net operating loss carryforwards indefinitely   21,300,000  
Federal | Research and Development      
Income Tax Disclosure [Line Items]      
Tax credit carryforwards   2,500,000  
State      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards   46,600,000  
State | Research and Development      
Income Tax Disclosure [Line Items]      
Tax credit carryforwards   $ 3,500,000  
Federal and State      
Income Tax Disclosure [Line Items]      
Net operating loss carryforwards expiration year   2038  
Federal and State | Research and Development      
Income Tax Disclosure [Line Items]      
Tax credit carryforwards expiration year   2038