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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (UNAUDITED) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Statement Of Income And Comprehensive Income [Abstract]        
Collaboration revenue $ 954,149   $ 2,703,998  
Operating expenses:        
Research and development 13,393,759 $ 4,946,611 31,667,396 $ 11,801,872
General and administrative 3,843,343 1,718,159 12,213,329 5,592,937
Total operating expenses 17,237,102 6,664,770 43,880,725 17,394,809
Loss from operations (16,282,953) (6,664,770) (41,176,727) (17,394,809)
Other income (expense):        
Change in fair value of convertible preferred stock tranche liability       (876,000)
Interest income 1,487,190 137,202 2,963,166 185,694
Total other income (expense) 1,487,190 137,202 2,963,166 (690,306)
Net loss and net loss attributable to common stockholders-basic and diluted $ (14,795,763) $ (6,527,568) $ (38,213,561) $ (18,085,115)
Net loss per share attributable to common stockholders-basic and diluted $ (0.40) $ (2.78) $ (1.48) $ (7.43)
Weighted-average common shares outstanding-basic and diluted 37,273,402 2,351,398 25,849,608 2,434,651