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Pay vs Performance Disclosure - USD ($)
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Pay vs Performance Disclosure      
Pay vs Performance Disclosure, Table

Pay Versus Performance

As required by Section 953(a) of the Dodd-Frank Wall Street Reform and Consumer Protection Act and Item 402(v) of Regulation S-K, we are providing information about the relationship between executive compensation actually paid to our PEO and the other named executive officers (as calculated in accordance with Item 402(v) of Regulation S-K).

Pay-Versus-Performance Table

 

Year

 

 

Summary
Compensation
Table Total
for First PEO(1)
($)

 

 

Summary
Compensation
Table Total
for Second PEO(1)
($)

 

 

Summary
Compensation
Table Total
for Third PEO(1)
($)

 

 

Compensation
Actually Paid
to First PEO (1),(2),(3)
($)

 

 

Compensation
Actually Paid
to Second PEO (1),(2),(3)
($)

 

 

Compensation
Actually Paid
to Third PEO (2),(3)
($)

 

 

Average
Summary
Compensation
Table Total
for Non-PEO
Named
Executive
Officers(1)
($)

 

 

Average
Compensation
Actually Paid
to Non-PEO
Named
Executive
Officers(1)(2)(3)
($)

 

 

Value of
Initial Fixed
$100
Investment
based on
TSR(4)
($)

 

 

Net
Income
(Loss)
($ millions)

 

 

2025

 

 

 

—

 

 

 

—

 

 

 

1,558,870

 

 

 

—

 

 

 

—

 

 

 

1,211,262

 

 

 

880,796

 

 

 

832,600

 

 

 

14.64

 

 

 

29.8

 

 

2024

 

 

 

—

 

 

 

758,139

 

 

 

6,003,238

 

 

 

—

 

 

 

708,392

 

 

 

2,086,532

 

 

 

2,201,749

 

 

 

2,013,072

 

 

 

15.17

 

 

 

(47.7

)

 

2023

 

 

 

1,804,303

 

 

 

786,463

 

 

 

—

 

 

 

1,152,826

 

 

 

610,490

 

 

 

—

 

 

 

728,062

 

 

 

570,724

 

 

 

48.25

 

 

 

(53.7

)

 

(1)
Albert Seymour, Ph.D. (“First PEO”) and Paul Alloway, Ph.D., J.D. (“Second PEO”) were our PEOs for 2023, Paul Alloway, Ph.D., J.D. (“Second PEO”) and Jodie Morrison (“Third PEO”) were our PEOs for 2024, while Jodie Morrison (“Third PEO”) was our PEO for 2025. The individuals comprising the Non-PEO named executive officers for each year presented are listed below.

 

2023

2024

2025

Charles Michaud, Jr.

Lee Kalowski

Lee Kalowski

W. Bradford Smith

Jason Campagna, M.D., Ph.D.

Shelia Violette, Ph.D.

Julie Jordan, M.D.

 

 
(2)
The amounts shown for Compensation Actually Paid have been calculated in accordance with Item 402(v) of Regulation S-K and do not reflect compensation actually earned, realized, or received by the Company’s named executive officers. These amounts reflect the Summary Compensation Table Total with certain adjustments as described in footnote 3 below.
(3)
Compensation Actually Paid reflects the exclusions and inclusions of certain amounts for the PEO and the Non-PEO named executive officers as set forth below. Equity values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column are the totals from the Stock Awards and Option Awards columns set forth in the Summary Compensation Table.

 

Year

 

Summary
Compensation
Table Total
for Third PEO
($)

 

 

Exclusion of Stock Awards
and Option Awards
 for Third PEO
($)

 

 

Inclusion of Equity
Values for Third PEO
($)

 

 

Compensation
Actually Paid
to Third PEO
($)

 

2025

 

 

1,558,870

 

 

 

(556,072

)

 

 

208,464

 

 

 

1,211,262

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Year

 

Average
Summary
Compensation
Table Total
for Non-PEO
Named
Executive
Officers
($)

 

 

Average Exclusion of
Stock Awards and
Option Awards
for Non-PEO
Named
Executive
Officers
($)

 

 

Average Inclusion of
Equity Values
for Non-PEO
Named
Executive
Officers
($)

 

 

Average Compensation
Actually Paid
to Non-PEO
Named
Executive
Officers
($)

 

2025

 

 

880,796

 

 

 

(163,469

)

 

 

115,273

 

 

 

832,600

 

 

The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables:

 

Year

 

Year-End Fair Value
of Equity Awards
Granted During Year
That Remained
Unvested as of Last
Day of Year for
Third PEO
($)

 

 

Change in Fair Value
from Last Day of
Prior Year to Last
Day of Year of
Unvested Equity
Awards for
Third PEO
($)

 

 

Vesting-Date
Fair Value of
Equity Awards
Granted During Year
that Vested During
Year for
Third PEO
($)

 

 

Change in Fair Value
from Last Day of
Prior Year to
Vesting Date of
Unvested Equity Awards
that Vested During
Year for
Third PEO
($)

 

 

Fair Value at
Last Day of
Prior Year of
Equity Awards
Forfeited During
Year for
Third PEO
($)

 

 

Total -
Inclusion of
Equity Values for
Third PEO
($)

 

2025

 

 

328,680

 

 

 

39,251

 

 

 

63,030

 

 

 

(222,497

)

 

 

—

 

 

 

208,464

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Year

 

Average
Year-End Fair Value
of Equity Awards
Granted During Year
That Remained
Unvested as of Last
Day of Year for
Non-PEO Named
Executive Officers
($)

 

 

Average
Change in Fair Value
from Last Day of
Prior Year to Last
Day of Year of
Unvested Equity
Awards for
Non-PEO Named
Executive Officers
($)

 

 

Average
Vesting-Date
Fair Value of
Equity Awards
Granted During Year
that Vested During
Year for
Non-PEO Named
Executive Officers
($)

 

 

Average
Change in Fair Value
from Last Day of
Prior Year to
Vesting Date of
Unvested Equity Awards
that Vested During
Year for
Non-PEO Named
Executive Officers
($)

 

 

Average
Fair Value at
Last Day of
Prior Year of
Equity Awards
Forfeited During
Year for
Non-PEO Named
Executive Officers
($)

 

 

Total -
Average
Inclusion of
Equity Values for
Non-PEO Named
Executive Officers
($)

 

2025

 

 

112,985

 

 

 

8,002

 

 

 

21,666

 

 

 

(27,380

)

 

 

—

 

 

 

115,273

 

 

(4)
The comparison assumes $100 was invested for the period starting December 31, 2022, through the end of the listed year, in the Company. Historical stock performance is not necessarily indicative of future stock performance.
(5)
The dollar amounts reported represent the amount of net income (loss) reflected in our audited financial statements for the applicable year.
    
Company Selected Measure Name NetIncome(Loss)    
Named Executive Officers, Footnote
(1)
Albert Seymour, Ph.D. (“First PEO”) and Paul Alloway, Ph.D., J.D. (“Second PEO”) were our PEOs for 2023, Paul Alloway, Ph.D., J.D. (“Second PEO”) and Jodie Morrison (“Third PEO”) were our PEOs for 2024, while Jodie Morrison (“Third PEO”) was our PEO for 2025. The individuals comprising the Non-PEO named executive officers for each year presented are listed below.

 

2023

2024

2025

Charles Michaud, Jr.

Lee Kalowski

Lee Kalowski

W. Bradford Smith

Jason Campagna, M.D., Ph.D.

Shelia Violette, Ph.D.

Julie Jordan, M.D.

 

 
   
Adjustment To PEO Compensation, Footnote
(3)
Compensation Actually Paid reflects the exclusions and inclusions of certain amounts for the PEO and the Non-PEO named executive officers as set forth below. Equity values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column are the totals from the Stock Awards and Option Awards columns set forth in the Summary Compensation Table.

 

Year

 

Summary
Compensation
Table Total
for Third PEO
($)

 

 

Exclusion of Stock Awards
and Option Awards
 for Third PEO
($)

 

 

Inclusion of Equity
Values for Third PEO
($)

 

 

Compensation
Actually Paid
to Third PEO
($)

 

2025

 

 

1,558,870

 

 

 

(556,072

)

 

 

208,464

 

 

 

1,211,262

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Year

 

Average
Summary
Compensation
Table Total
for Non-PEO
Named
Executive
Officers
($)

 

 

Average Exclusion of
Stock Awards and
Option Awards
for Non-PEO
Named
Executive
Officers
($)

 

 

Average Inclusion of
Equity Values
for Non-PEO
Named
Executive
Officers
($)

 

 

Average Compensation
Actually Paid
to Non-PEO
Named
Executive
Officers
($)

 

2025

 

 

880,796

 

 

 

(163,469

)

 

 

115,273

 

 

 

832,600

 

 

The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables:

 

Year

 

Year-End Fair Value
of Equity Awards
Granted During Year
That Remained
Unvested as of Last
Day of Year for
Third PEO
($)

 

 

Change in Fair Value
from Last Day of
Prior Year to Last
Day of Year of
Unvested Equity
Awards for
Third PEO
($)

 

 

Vesting-Date
Fair Value of
Equity Awards
Granted During Year
that Vested During
Year for
Third PEO
($)

 

 

Change in Fair Value
from Last Day of
Prior Year to
Vesting Date of
Unvested Equity Awards
that Vested During
Year for
Third PEO
($)

 

 

Fair Value at
Last Day of
Prior Year of
Equity Awards
Forfeited During
Year for
Third PEO
($)

 

 

Total -
Inclusion of
Equity Values for
Third PEO
($)

 

2025

 

 

328,680

 

 

 

39,251

 

 

 

63,030

 

 

 

(222,497

)

 

 

—

 

 

 

208,464

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Year

 

Average
Year-End Fair Value
of Equity Awards
Granted During Year
That Remained
Unvested as of Last
Day of Year for
Non-PEO Named
Executive Officers
($)

 

 

Average
Change in Fair Value
from Last Day of
Prior Year to Last
Day of Year of
Unvested Equity
Awards for
Non-PEO Named
Executive Officers
($)

 

 

Average
Vesting-Date
Fair Value of
Equity Awards
Granted During Year
that Vested During
Year for
Non-PEO Named
Executive Officers
($)

 

 

Average
Change in Fair Value
from Last Day of
Prior Year to
Vesting Date of
Unvested Equity Awards
that Vested During
Year for
Non-PEO Named
Executive Officers
($)

 

 

Average
Fair Value at
Last Day of
Prior Year of
Equity Awards
Forfeited During
Year for
Non-PEO Named
Executive Officers
($)

 

 

Total -
Average
Inclusion of
Equity Values for
Non-PEO Named
Executive Officers
($)

 

2025

 

 

112,985

 

 

 

8,002

 

 

 

21,666

 

 

 

(27,380

)

 

 

—

 

 

 

115,273

 
   
Non-PEO NEO Average Total Compensation Amount $ 880,796 $ 2,201,749 $ 728,062
Non-PEO NEO Average Compensation Actually Paid Amount $ 832,600 2,013,072 570,724
Adjustment to Non-PEO NEO Compensation Footnote
(3)
Compensation Actually Paid reflects the exclusions and inclusions of certain amounts for the PEO and the Non-PEO named executive officers as set forth below. Equity values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column are the totals from the Stock Awards and Option Awards columns set forth in the Summary Compensation Table.

 

Year

 

Summary
Compensation
Table Total
for Third PEO
($)

 

 

Exclusion of Stock Awards
and Option Awards
 for Third PEO
($)

 

 

Inclusion of Equity
Values for Third PEO
($)

 

 

Compensation
Actually Paid
to Third PEO
($)

 

2025

 

 

1,558,870

 

 

 

(556,072

)

 

 

208,464

 

 

 

1,211,262

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Year

 

Average
Summary
Compensation
Table Total
for Non-PEO
Named
Executive
Officers
($)

 

 

Average Exclusion of
Stock Awards and
Option Awards
for Non-PEO
Named
Executive
Officers
($)

 

 

Average Inclusion of
Equity Values
for Non-PEO
Named
Executive
Officers
($)

 

 

Average Compensation
Actually Paid
to Non-PEO
Named
Executive
Officers
($)

 

2025

 

 

880,796

 

 

 

(163,469

)

 

 

115,273

 

 

 

832,600

 

 

The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables:

 

Year

 

Year-End Fair Value
of Equity Awards
Granted During Year
That Remained
Unvested as of Last
Day of Year for
Third PEO
($)

 

 

Change in Fair Value
from Last Day of
Prior Year to Last
Day of Year of
Unvested Equity
Awards for
Third PEO
($)

 

 

Vesting-Date
Fair Value of
Equity Awards
Granted During Year
that Vested During
Year for
Third PEO
($)

 

 

Change in Fair Value
from Last Day of
Prior Year to
Vesting Date of
Unvested Equity Awards
that Vested During
Year for
Third PEO
($)

 

 

Fair Value at
Last Day of
Prior Year of
Equity Awards
Forfeited During
Year for
Third PEO
($)

 

 

Total -
Inclusion of
Equity Values for
Third PEO
($)

 

2025

 

 

328,680

 

 

 

39,251

 

 

 

63,030

 

 

 

(222,497

)

 

 

—

 

 

 

208,464

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Year

 

Average
Year-End Fair Value
of Equity Awards
Granted During Year
That Remained
Unvested as of Last
Day of Year for
Non-PEO Named
Executive Officers
($)

 

 

Average
Change in Fair Value
from Last Day of
Prior Year to Last
Day of Year of
Unvested Equity
Awards for
Non-PEO Named
Executive Officers
($)

 

 

Average
Vesting-Date
Fair Value of
Equity Awards
Granted During Year
that Vested During
Year for
Non-PEO Named
Executive Officers
($)

 

 

Average
Change in Fair Value
from Last Day of
Prior Year to
Vesting Date of
Unvested Equity Awards
that Vested During
Year for
Non-PEO Named
Executive Officers
($)

 

 

Average
Fair Value at
Last Day of
Prior Year of
Equity Awards
Forfeited During
Year for
Non-PEO Named
Executive Officers
($)

 

 

Total -
Average
Inclusion of
Equity Values for
Non-PEO Named
Executive Officers
($)

 

2025

 

 

112,985

 

 

 

8,002

 

 

 

21,666

 

 

 

(27,380

)

 

 

—

 

 

 

115,273

 
   
Compensation Actually Paid vs. Total Shareholder Return

Relationship Between PEO and Non-PEO Named Executive Officer Compensation Actually Paid and Company Total Stockholder Return (“TSR”)

The following chart sets forth the relationship between Compensation Actually Paid to our PEOs, the average of Compensation Actually Paid to our Non-PEO named executive officers, and the Company’s cumulative TSR over the three most recently completed fiscal years.

 

img106090300_2.gif

    
Compensation Actually Paid vs. Net Income

Relationship Between PEO and Non-PEO Named Executive Officer Compensation Actually Paid and Net Income (Loss)

The following chart sets forth the relationship between Compensation Actually Paid to our PEOs, the average of Compensation Actually Paid to our Non-PEO named executive officers, and our net income (loss) during the three most recently completed fiscal years.

 

img106090300_3.gif

    
Total Shareholder Return Amount $ 14.64 1,517 4,825
Net Income (Loss) $ 29,800,000 (47,700,000) (53,700,000)
Additional 402(v) Disclosure
(2)
The amounts shown for Compensation Actually Paid have been calculated in accordance with Item 402(v) of Regulation S-K and do not reflect compensation actually earned, realized, or received by the Company’s named executive officers. These amounts reflect the Summary Compensation Table Total with certain adjustments as described in footnote 3 below.
    
Albert Seymour, Ph.D. [Member]      
Pay vs Performance Disclosure      
PEO Total Compensation Amount $ 0 0 1,804,303
PEO Actually Paid Compensation Amount 0 0 $ 1,152,826
PEO Name     Albert Seymour, Ph.D.
Paul Alloway, Ph.D., J.D. [Member]      
Pay vs Performance Disclosure      
PEO Total Compensation Amount 0 758,139 $ 786,463
PEO Actually Paid Compensation Amount 0 $ 708,392 $ 610,490
PEO Name   Paul Alloway, Ph.D., J.D. Paul Alloway, Ph.D., J.D.
Jodie Morrison [Member]      
Pay vs Performance Disclosure      
PEO Total Compensation Amount 1,558,870 $ 6,003,238 $ 0
PEO Actually Paid Compensation Amount $ 1,211,262 $ 2,086,532 $ 0
PEO Name Jodie Morrison Jodie Morrison  
PEO | Jodie Morrison [Member] | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount $ (556,072)    
PEO | Jodie Morrison [Member] | Equity Awards Adjustments, Excluding Value Reported in Compensation Table      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 208,464    
PEO | Jodie Morrison [Member] | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 328,680    
PEO | Jodie Morrison [Member] | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 39,251    
PEO | Jodie Morrison [Member] | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 63,030    
PEO | Jodie Morrison [Member] | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 222,497    
PEO | Jodie Morrison [Member] | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0    
Non-PEO NEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (163,469)    
Non-PEO NEO | Equity Awards Adjustments, Excluding Value Reported in Compensation Table      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 115,273    
Non-PEO NEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 112,985    
Non-PEO NEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 8,002    
Non-PEO NEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 21,666    
Non-PEO NEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (27,380)    
Non-PEO NEO | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount $ 0