Agreements with Horizon - Additional Information (Detail) - USD ($) $ in Millions		12 Months Ended
	Nov. 07, 2025	Dec. 31, 2025	Dec. 31, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Common stock shares issued		12,858,047	12,197,615
Horizon collaboration agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaboration agreement, transaction price		$ 55.0
Collaboration agreement, Aggregate amount of sales milestone	$ 75.1	75.1
Received amount from Horizon	55.0	55.0
Milestone Payment Based on Approval		5.0
Collaboration agreement, contingent payment		75.1
Refund liability	$ 55.0	55.0
Common stock shares issued	553,695
Payment to horizon		20.1
Legacy Q32
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Business combination, intial consideration		55.0
Maximum [Member] | Horizon collaboration agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Annual net sales threshold trigger		1,500.0
Minimum [Member] | Horizon collaboration agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Annual net sales threshold trigger		250.0
Sales-based milestone | Horizon collaboration agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaboration agreement, contingent payment		75.1
Collaboration agreement, contingent payment payable excess of cash received		$ 70.1