Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Payables and Accruals [Abstract]
Accrued compensation and related expenses	$ 2,486	$ 2,782
Accrued external research and development	462	2,611
Accrued professional services and other	591	1,474
Operating lease liability, current	693	612
Total accrued expenses and other current liabilities	$ 4,232	$ 7,479
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]	Accrued Expenses And Other Liabilities Current	Accrued Expenses And Other Liabilities Current