Property and Equipment, Net - Schedule of Property Plant and Equipment (Detail) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Property Plant and Equipment [Line Items]
Total property and equipment	$ 2,823	$ 2,823
Less accumulated depreciation	(1,844)	(1,453)
Property and equipment, net	979	1,370
Lab equipment [Member]
Property Plant and Equipment [Line Items]
Total property and equipment	1,382	1,382
Furniture and fixtures [Member]
Property Plant and Equipment [Line Items]
Total property and equipment	351	351
Computer equipment [Member]
Property Plant and Equipment [Line Items]
Total property and equipment	89	89
Leasehold improvements [Member]
Property Plant and Equipment [Line Items]
Total property and equipment	$ 1,001	$ 1,001