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License Agreements - Additional Information (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2016
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Dec. 31, 2022
Dec. 31, 2021
License Agreement [Line Items]              
Collaboration agreement revenue recognized   $ 0 $ 802 $ 1,156 $ 2,406 $ 3,208 $ 33,971
City of Hope              
License Agreement [Line Items]              
Annual license fee           25,000  
City of Hope | Maximum              
License Agreement [Line Items]              
Development and commercialization milestone payment           3,200  
City of Hope | January 2023              
License Agreement [Line Items]              
Amount paid to related party upon dosing the first patient           50,000  
California Institute Of Technology | Maximum | Co Exclusive License Agreement              
License Agreement [Line Items]              
Development and regulatory milestone payments $ 7,200            
California Institute Of Technology | Minimum | Co Exclusive License Agreement              
License Agreement [Line Items]              
Annual minimal royalty fee $ 20,000            
Novartis              
License Agreement [Line Items]              
Collaboration agreement revenue recognized             26,900
Novartis | Collaborative Arrangement              
License Agreement [Line Items]              
Collaboration revenue             0
Collaboration agreement revenue recognized             30,800
Deferred revenue           0 0
Accounts receivable           $ 0 0
Novartis | Collaborative Arrangement | Deferred Revenue              
License Agreement [Line Items]              
Collaboration agreement revenue recognized             $ 30,200