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Segment Reporting - Summary of the Company's segment expenses (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Segment Reporting Information [Line Items]    
Personnel-related costs (excluding stock-based compensation) $ 16,122 $ 13,166
Other G&A expenses 9,586 5,824
Interest (income) expense, net (2,832) (693)
Other segment items [1] (9,978) 15,645
Total Segment Net Loss 47,733 53,743
ADX Zero Nine Seven [Member]    
Segment Reporting Information [Line Items]    
Direct research and development expense 5,253 7,185
Bempikibart [Member]    
Segment Reporting Information [Line Items]    
Direct research and development expense 28,726 11,722
Discovery and Other [Member]    
Segment Reporting Information [Line Items]    
Direct research and development expense $ 856 $ 894
[1]

(1) Other segment items are included in order to reconcile to total segment net loss. Other segment items include non-cash items such as depreciation and amortization expense and stock-based compensation expense, gains and losses on the change in fair value of convertible notes, change in fair value of contingent value rights and loss from equity method investment. In 2023, other segment items also includes the reversal of collaboration arrangement revenue related to the termination of the Horizon Agreement (see Note 15).