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Nature of the Business - Additional Information (Detail) - USD ($)
$ in Thousands
12 Months Ended
Mar. 25, 2024
Dec. 31, 2024
Dec. 31, 2023
Nov. 16, 2023
Nature Of Business [Line Items]        
Common stock, aggregate purchase price       $ 42,000
Net Income (Loss)   $ (47,733) $ (53,743)  
Accumulated deficit   (234,814) (187,081)  
Cash and cash equivalents   77,965 $ 25,617  
Homology        
Nature Of Business [Line Items]        
Business combination shares conversion into rights to purchase common stock 1,682,045      
Stockholders' equity, reverse stock split one-for-eighteen      
Outstanding common stock of the combined company 74.40%      
Conversion of Stock, Shares Converted 7,017,842      
Parent company [Member]        
Nature Of Business [Line Items]        
Cash and cash equivalents   $ 78,000