Annual rent operating lease aggregate after increase.

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Commercial milestone payment payable.

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Commitment and contingencies.

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Development and sales milestone payment payable.

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- Definition

Lessee operating lease not yet commenced increase in percentage of base rent.

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- Definition

percentage of sublicense fees.

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Period of obligation to pay royalties.

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Royalty as a percentage of net sales.

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- Definition

Sublease aggregate base rent obligation.

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Upfront payment made.

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- Definition

Area of a real estate property.

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Amount of incentive received by lessee from lessor.

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Date which lease or group of leases is set to expire, in YYYY-MM-DD format.

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Term of lessee's operating lease renewal for lease not yet commenced, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Present value of lessee's discounted obligation for lease payments from operating lease, classified as current.

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Weighted average discount rate for operating lease calculated at point in time.

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Weighted average remaining lease term for operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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- Definition

The amount of the write-off for research and development assets that were acquired in a transaction other than a business combination.

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The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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The amount of an asset, typically cash, provided to a counterparty to provide certain assurance of performance by the entity pursuant to the terms of a written or oral agreement, such as a lease.

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Carrying amount (including both current and noncurrent portions) of accrued known and estimated losses incurred as of the balance sheet date for which no insurance coverage exists, and for which a claim has been made or is probable of being asserted, typically arising from workmen's compensation-type of incidents and personal injury to nonemployees from accidents on the entity's property.

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Number of shares of stock issued during the period as part of a transaction to acquire assets that do not qualify as a business combination.

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Commitments and Contingencies - Additional Information (Detail) $ in Thousands	1 Months Ended	3 Months Ended		4 Months Ended	12 Months Ended
	Dec. 31, 2021 USD ($) ft²	Mar. 31, 2024 USD ($)	Mar. 31, 2023 USD ($)	Dec. 31, 2019 USD ($) shares	Dec. 31, 2023 USD ($)	Dec. 31, 2021 USD ($) ft²	Dec. 31, 2019 USD ($)	Dec. 31, 2022 USD ($)	Sep. 30, 2019 USD ($)
Commitment And Contingencies [Line Items]
Lease expiration date						Dec. 31, 2031
Operating lease liability, current		$ 1,560			$ 538
Research and development expenses		9,841	$ 7,910
Executive insurance reserve		5,000
License Agreement With The University Of Colorado [Member]
Commitment And Contingencies [Line Items]
Development and sales milestone payment payable		$ 2,200
Percentage of sublicense fees		15.00%
Period of obligation to pay royalties		20 years
Research and development expenses		$ 0			$ 0
License Agreement With Bristol Mayers Equib Company [Member]
Commitment And Contingencies [Line Items]
Percentage of sublicense fees				60.00%
Period of obligation to pay royalties				12 years
Upfront payment made				$ 8,000
Commercial milestone payment payable				$ 215,000			$ 215,000
Royalty as a percentage of sales				10.00%
In process research and development expense recognized							14,600
License Agreement With Bristol Mayers Equib Company [Member] \| Cash Consideration [Member]
Commitment And Contingencies [Line Items]
In process research and development expense recognized							8,000
License Agreement With Bristol Mayers Equib Company [Member] \| Temporary Equity [Member]
Commitment And Contingencies [Line Items]
In process research and development expense recognized							$ 6,600
License Agreement With Bristol Mayers Equib Company [Member] \| Maximum [Member] \| Tranche Three [Member]
Commitment And Contingencies [Line Items]
Development and sales milestone payment payable									$ 49,000
License Agreement With Bristol Mayers Equib Company [Member] \| Minimum [Member] \| Tranche Three [Member]
Commitment And Contingencies [Line Items]
Development and sales milestone payment payable									$ 32,000
License Agreement With Bristol Mayers Equib Company [Member] \| Series A Redeemable Preferred Stock [Member]
Commitment And Contingencies [Line Items]
Stock issued during period shares purchase of assets \| shares				6,628,788
Waltham Massauchets [Member]
Commitment And Contingencies [Line Items]
Office space leased \| ft²	15,000					15,000
Lessee, operating lease, lease not yet commenced, renewal term	5 years					5 years
Sublease aggregate base rent obligation	$ 970					$ 970
Percentage increase in initial annual base rent per square foot.	3.00%
Annual Rent Operating lease Aggregate After Increase	$ 11,100
Security deposit								$ 647
Operating lease weighted average remaining lease term		7 years 9 months
Operating lease weighted average discount rate		7.50%
Operating lease liability, current		$ 1,000
Waltham Massauchets [Member] \| Restricted Cash And Cash Equivalents Non Current [Member]
Commitment And Contingencies [Line Items]
Lessee tenant improvement allowance								$ 400