CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Cash flows from operating activities:
Net loss	$ (5,005)	$ (95,764)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	1,293	8,353
Noncash lease expense	1,306	1,191
Loss from equity method investment	(5,488)	0
Stock-based compensation expense	13,054	17,245
(Accretion of discount) amortization of premium on short-term investments	(1,947)	(894)
Loss on disposal of property and equipment	49	133
Gain on sale of business	(131,249)	0
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	840	(4,996)
Accounts payable	(981)	(2,487)
Accrued expenses and other liabilities	7,418	1,500
Deferred revenue	(3,208)	(33,411)
Operating lease liabilities	(719)	(2,409)
Net cash used in operating activities	(113,661)	(109,751)
Cash flows from investing activities:
Purchases of short-term investments	(157,460)	(97,392)
Maturities of short-term investments	65,461	49,000
Proceeds from sale of business	130,000	0
Purchases of property and equipment	(1,285)	(2,396)
Net cash provided by (used in) investing activities	36,716	(50,788)
Cash flows from financing activities:
Proceeds from issuance of common stock in follow-on public offering, net of discounts and issuance costs	0	49,744
Proceeds from issuance of common stock pursuant to ATM financing, net of discounts and issuance costs	0	1,454
Proceeds from issuance of common stock from option exercises	1	145
Proceeds from issuance of common stock pursuant to employee stock purchase plan	595	826
Net cash provided by financing activities	596	52,169
Net change in cash, cash equivalents and restricted cash	(76,349)	(108,370)
Cash, cash equivalents and restricted cash, beginning of period	110,335	218,705
Cash, cash equivalents and restricted cash, end of period	33,986	110,335
Supplemental disclosures of noncash investing and financing activities:
Cash paid for income taxes	720	0
Reclassification of liability for common stock vested	0	13
Property and equipment additions included in accounts payable	0	241
Property and equipment additions included in accrued expenses and other liabilities	8	116
Unrealized loss on available for sale securities, net	$ (397)	$ (7)