Commitments and Contingencies - Additional Information (Details) $ in Thousands	1 Months Ended				12 Months Ended
	Feb. 28, 2022 USD ($)	Dec. 31, 2017 ft² Phase $ / ft²	Nov. 30, 2017 USD ($) ft²	Sep. 30, 2016	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)	Sep. 30, 2022
Commitment And Contingencies [Line Items]
Sublease aggregate base rent obligation					$ 2,700
Tenant improvement allowance			$ 6,300
Increase decrease in right-of-use asset	$ 200				10,900
Sublease income					1,979	$ 861
Security deposit					0	2,000
Right-of-use assets					20,563	$ 15,607
OXB Solutions
Commitment And Contingencies [Line Items]
Increase decrease in right-of-use asset					6,100
Sublease income					2,000
Tenant improvement allowances							100.00%
Maximum
Commitment And Contingencies [Line Items]
Tenant improvement allowance					10,900
Bedford, Massachusetts
Commitment And Contingencies [Line Items]
Operating lease beginning year and month				2016-11
Operating lease expiration year and month		2027-02	2027-02	2021-10
Operating lease agreements additional term				3 years
Sublease aggregate base rent obligation			$ 1,400		$ 4,700
Office space leased | ft²		67,000	23,011
Lessee, operating lease, lease not yet commenced, renewal term		5 years
Number of phases | Phase		2
Initial annual base rent per square foot | $ / ft²		39.50
Percentage increase in initial annual base rent per square foot.		3.00%	3.00%
Bedford, Massachusetts | Phase One
Commitment And Contingencies [Line Items]
Office space leased | ft²		46,000
Rent due date		2018-09
Bedford, Massachusetts | Phase Two
Commitment And Contingencies [Line Items]
Office space leased | ft²		21,000
Rent due date		2019-03