CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (UNAUDITED) - USD ($)	Total	Equity Method Investee	Follow-on Offering [Member]	Common Stock	Common Stock Follow-on Offering [Member]	Additional Paid-in Capital	Additional Paid-in Capital Equity Method Investee	Additional Paid-in Capital Follow-on Offering [Member]	Accumulated Other Comprehensive Gain (Loss)	Accumulated Deficit
Beginning balance at Dec. 31, 2020	$ 195,995,000			$ 5,000		$ 524,358,000				$ (328,368,000)
Beginning balance, Shares at Dec. 31, 2020				50,265,575
Issuance of common stock, net of discounts and issuance costs	1,454,000					1,454,000
Issuance of common stock, net of discounts and issuance costs, Share				114,914
Issuance of common stock in follow-on offering, net of discounts and issuance costs	1,454,000					1,454,000
Issuance of common stock, net of discounts and issuance costs, Shares				114,914
Vesting of common stock from option exercises	4,000					4,000
Vesting of common stock from option exercises, Shares				1,011
Issuance of common stock from option exercises	143,000					143,000
Issuance of common stock from option exercises, Shares				55,277
Issuance of common stock pursuant to employee stock purchase plan	446,000					446,000
Issuance of common stock pursuant to employee stock purchase plan, Shares				48,792
Stock-based compensation	3,883,000					3,883,000
Other comprehensive gain (loss)	(23,000)								$ (23,000)
Net income (loss)	(1,073,000)									(1,073,000)
Ending balance at Mar. 31, 2021	200,829,000			$ 5,000		530,288,000			(23,000)	(329,441,000)
Ending balance, Shares at Mar. 31, 2021				50,485,569
Beginning balance at Dec. 31, 2020	195,995,000			$ 5,000		524,358,000				(328,368,000)
Beginning balance, Shares at Dec. 31, 2020				50,265,575
Other comprehensive gain (loss)	2,000
Net income (loss)	(31,573,000)
Ending balance at Jun. 30, 2021	224,577,000			$ 6,000		584,510,000			2,000	(359,941,000)
Ending balance, Shares at Jun. 30, 2021				57,086,957
Beginning balance at Mar. 31, 2021	200,829,000			$ 5,000		530,288,000			(23,000)	(329,441,000)
Beginning balance, Shares at Mar. 31, 2021				50,485,569
Issuance of common stock, net of discounts and issuance costs			$ 49,744,000		$ 1,000			$ 49,743,000
Issuance of common stock, net of discounts and issuance costs, Share					6,596,306
Issuance of common stock in follow-on offering, net of discounts and issuance costs			$ 49,744,000		$ 1,000			$ 49,743,000
Issuance of common stock, net of discounts and issuance costs, Shares					6,596,306
Vesting of common stock from option exercises	4,000					4,000
Vesting of common stock from option exercises, Shares				1,011
Issuance of common stock from option exercises	2,000					2,000
Issuance of common stock from option exercises, Shares				4,071
Stock-based compensation	4,473,000					4,473,000
Other comprehensive gain (loss)	25,000								25,000
Net income (loss)	(30,500,000)									(30,500,000)
Ending balance at Jun. 30, 2021	224,577,000			$ 6,000		584,510,000			2,000	(359,941,000)
Ending balance, Shares at Jun. 30, 2021				57,086,957
Beginning balance at Dec. 31, 2021	169,651,000			$ 6,000		593,784,000			(7,000)	(424,132,000)
Beginning balance, Shares at Dec. 31, 2021				57,150,274
Issuance of common stock from RSU vesting				$ 87,140,000
Issuance of common stock from option exercises	1,000					1,000
Issuance of common stock from option exercises, Shares				293
Issuance of common stock pursuant to employee stock purchase plan	439,000					439,000
Issuance of common stock pursuant to employee stock purchase plan, Shares				147,871
Stock-based compensation	4,051,000					4,051,000
Other comprehensive gain (loss)	7,000								7,000
Net income (loss)	92,105,000									92,105,000
Ending balance at Mar. 31, 2022	266,254,000			$ 6,000		598,275,000				(332,027,000)
Ending balance, Shares at Mar. 31, 2022				57,385,578
Beginning balance at Dec. 31, 2021	169,651,000			$ 6,000		593,784,000			(7,000)	(424,132,000)
Beginning balance, Shares at Dec. 31, 2021				57,150,274
Other comprehensive gain (loss)	(34,000)
Net income (loss)	63,016,000
Ending balance at Jun. 30, 2022	240,288,000			$ 6,000		601,439,000			(41,000)	(361,116,000)
Ending balance, Shares at Jun. 30, 2022				57,385,578
Beginning balance at Mar. 31, 2022	266,254,000			$ 6,000		598,275,000				(332,027,000)
Beginning balance, Shares at Mar. 31, 2022				57,385,578
Stock-based compensation	3,143,000	$ 21,000				3,143,000	$ 21,000
Other comprehensive gain (loss)	(41,000)								(41,000)
Net income (loss)	(29,089,000)									(29,089,000)
Ending balance at Jun. 30, 2022	$ 240,288,000			$ 6,000		$ 601,439,000			$ (41,000)	$ (361,116,000)
Ending balance, Shares at Jun. 30, 2022				57,385,578