Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum Expected volatility, maximum Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period Stock option vesting period Forecast Forecast [Member] Lease expiration date year and month. Lease Expiration Date Year And Month Operating lease expiration year and month Transferred units, value Stock Issued During Period, Value, Conversion of Units Operating Expenses [Abstract] Operating expenses: Operating Income (Loss) Loss from operations Increase in Lease Liability Increase (Decrease) in Operating Lease Liability Follow-on offering . Follow On Offering [Member] Follow-on Offering [Member] Supply Agreement [Member] Supply Agreement [Member] Entity Emerging Growth Company Entity Emerging Growth Company Proceeds from Stock Plans Proceeds from issuance of common stock pursuant to employee stock purchase plan Aggregate proceeds from shares issued under the plan Equity Method Investment, Summarized Financial Information [Abstract] Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets, Total Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant Number of shares outstanding available for future grant Marketable Securities, Policy [Policy Text Block] Short-Term Investments Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment, Total Geographical [Axis] Geographical Common stock, $0.0001 par value; 200,000,000 shares authorized; 57,385,578 and 57,150,274 shares issued and outstanding as of March 31, 2022 and December 31, 2021, respectively Common Stock, Value, Issued Common Stock, Value, Issued, Total Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Ending Balance Entity Address, State or Province Entity Address, State or Province Common stock purchase agreement condition. Common Stock Purchase Agreement Condition Common stock purchase agreement condition Tax positions, description Income Tax Examination, Likelihood of Unfavorable Settlement Liabilities Total liabilities Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Maximum shares allowed to be issued under ESPP. Maximum Shares Allowed To Be Issued Under E S P P Maximum shares allowed to be issued under ESPP Sublease aggregate base rent obligation. Sublease Aggregate Base Rent Obligation Sublease aggregate base rent obligation Sublease Income Sublease income At the market sales agreement. At The Market Sales Agreement [Member] ATM Organization consolidation and presentation of financial statements. Organization Consolidation And Presentation Of Financial Statements [Table] Organization Consolidation And Presentation Of Financial Statements [Table] OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Change in unrealized gain (loss) on available for sale securities, net Unrealized gain (loss) on available for sale securities, net Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Legal Entity [Axis] Schedule of cash, cash equivalents and available-for-sale securities. Schedule Of Cash Cash Equivalents And Available For Sale Securities [Table] Schedule Of Cash Cash Equivalents And Available For Sale Securities [Table] Collaboration revenue. Collaboration Revenue Collaboration Revenue General and Administrative Expense [Member] General and Administrative Operating Lease, Lease Income, Lease Payments Cash paid for amounts included in the measurement of lease liabilities Weighted Average Remaining Contractual Term, Exercisable at March 31, 2022 Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Restricted Cash Restricted cash Restricted Cash, Total Accounts Receivable, after Allowance for Credit Loss, Current Accounts receivable Accounts Receivable, after Allowance for Credit Loss, Current, Total Short-term investments Debt Securities, Available-for-sale, Current Short-term investments Debt Securities, Available-for-sale, Current, Total Fair Value, Recurring and Nonrecurring [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Significant Accounting Policies [Text Block] SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES Schedule of Related Party Transactions, by Related Party [Table] City Area Code City Area Code Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule of Stock Options Valuation Assumptions Using a Black-Scholes Option Pricing Model Upfront Payment Received Upfront Payment Received Upfront Payment Received Investment maturity term. Investment Maturity Term Contractual maturity date of investments Contract with Customer, Liability Deferred revenue Contract with Customer, Liability, Total Commitments and contingencies (Note 8) Commitments and Contingencies Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of Anti-dilutive Effect Excluded from Computation of Diluted Net Loss Per Share Attributable to Common Stockholders Issuance of common stock, net of discounts and issuance costs, Share Stock Issued During Period, Shares, New Issues Issuance of common stock, net of discounts and issuance costs, Shares Debt Securities, Available-for-sale Cash equivalents and short-term investments, Fair Value Debt Securities, Available-for-sale, Total Allowed annual percentage increase in shares authorized as percentage of outstanding shares of common stock. Allowed Annual Percentage Increase In Shares Authorized As Percentage Of Outstanding Shares Of Common Stock Allowed annual percentage increase in shares authorized as percentage of outstanding shares of common stock Scenario [Axis] Share-based Payment Arrangement, Disclosure [Abstract] Basis of Accounting, Policy [Policy Text Block] Basis of Presentation Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of common stock pursuant to employee stock purchase plan, Shares Number of shares issued to the plan Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents Total cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Beginning Balance Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Ending Balance Related Party [Domain] Related Party Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Other income (expense): Other Nonoperating Income (Expense) [Abstract] Net Cash Provided by (Used in) Investing Activities Net cash (used in) provided by investing activities Capital Expenditures Incurred but Not yet Paid Property and equipment additions included in accounts payable Equity Securities Purchase Agreement Equity Unit Purchase Agreements [Member] Employee-related Liabilities, Current Accrued compensation and benefits Employee-related Liabilities, Current, Total General and Administrative Expense, Total General and Administrative Expense General and administrative Property, Plant and Equipment, Net Property and equipment, net Property and equipment, net Property, Plant and Equipment, Net, Beginning Balance Property, Plant and Equipment, Net, Ending Balance Contract with Customer, Liability, Current Deferred revenue Common Stock, Shares, Issued Common stock, shares issued Common Stock, Shares, Issued, Total Statement of Comprehensive Income [Abstract] Stock purchase agreement remaining allocated value. Stock Purchase Agreement Remaining Allocated Value Stock purchase agreement remaining allocated value Debt Securities, Available-for-sale, Amortized Cost Cash equivalents and short-term investments, Amortized Cost Operating Lease, Right-of-Use Asset Right-of-use assets Share based compensation arrangement by share based payment award fair value assumptions fair value of common stock. Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Fair Value Of Common Stock Underlying common stock fair value Security Exchange Name Security Exchange Name Statistical Measurement [Domain] Statistical Measurement Furniture and Fixtures [Member] Furniture and Fixtures Gain on sale of business Gain on sale of business Gain on sale of business Gain (Loss) on Disposition of Business Cash and Cash Equivalents, Fair Value Disclosure Cash equivalents, fair value Document Period End Date Document Period End Date Income Statement Location [Axis] Income Statement Location Investments [Domain] Investments Maximum shares allowed to be issued. Maximum Shares Allowed To Be Issued Maximum shares of common stock may be issued Common Stock, Shares Authorized Common stock, shares authorized Lessee, Sublease, Extend Term Lessee sublease extend term. Sublease extended term Use of Estimates, Policy [Policy Text Block] Use of Estimates Operating Lease, Liability, Current Operating lease liabilities Amortization of premium on short-term investments Accretion (Amortization) of Discounts and Premiums, Investments Related Party [Axis] Related Party Equity method investment, description of principal activities Equity Method Investment, Description of Principal Activities Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Anti-dilutive securities Anti-dilutive securities Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Property and equipment additions included in accrued expenses and other liabilities. Property And Equipment Additions Included In Accrued Expenses And Other Liabilities Property and equipment additions included in accrued expenses and other liabilities Asset not yet in service. Asset Not Yet In Service [Member] Assets Not Yet in Service Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Schedule of Assets Measured at Fair Value on Recurring Basis Current Fiscal Year End Date Current Fiscal Year End Date Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Net change in cash, cash equivalents and restricted cash Unvested common shares subject to repurchase repurchased. Unvested Common Shares Subject To Repurchase Repurchased Repurchased Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Period Remaining performance obligation, expected timing of satisfaction, period Operating Lease, Cost Operating lease costs Phase one. Phase One [Member] Phase One Equity method investment, ownership percentage Equity Method Investment, Ownership Percentage Contributed cash Limited Partners' Contributed Capital Counterparty Name [Axis] Counterparty Name Assets [Abstract] Assets Proceeds from sale of business Proceeds from sale of business Accrued income taxes Increase (Decrease) in Income Taxes Payable Stock Issued During Period, Shares, Conversion of Convertible Securities Conversion of convertible preferred stock into common stock upon initial public offering, Shares Business Description and Basis of Presentation [Text Block] NATURE OF BUSINESS AND BASIS OF PRESENTATION 2023 Lessee, Operating Lease, Liability, to be Paid, Year One Accounts Payable, Current Accounts payable Accounts Payable, Current, Total Issuance of common stock from RSU vesting Issuance of common stock from RSU vesting Private Placement [Member] Private Placement Common Stock, Par or Stated Value Per Share Common stock, par value Weighted-average common shares outstanding-basic Weighted Average Number of Shares Outstanding, Basic Weighted Average Number of Shares Outstanding, Basic, Total Shares, Outstanding Ending balance, Shares Beginning balance, Shares Additional Paid in Capital, Common Stock Additional paid-in capital Additional Paid in Capital, Common Stock, Beginning Balance Additional Paid in Capital, Common Stock, Ending Balance Assets held for sale Assets Held-for-sale, Not Part of Disposal Group, Current Assets Held-for-sale, Not Part of Disposal Group, Current, Total Research and Development Expense, Policy [Policy Text Block] Research and Development Costs Cash, Cash Equivalents and Investments [Table Text Block] Summary of Short Term Investments Income (loss) before income taxes Income (loss) before income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest OXB Solutions OXB Solutions [Member] OXB Solutions [Member] Document Type Document Type Preferred stock, $0.0001 par value, 10,000,000 shares authorized; no shares issued and outstanding at March 31, 2022 and December 31, 2021 Preferred Stock, Value, Issued Preferred Stock, Value, Issued, Total Preferred Stock, Value, Issued, Beginning Balance Preferred Stock, Value, Issued, Ending Balance Operating Lease, Liability, Noncurrent Operating lease liabilities, net of current portion Schedule of Accrued Liabilities [Table Text Block] Schedule of Accrued Expenses and Other Liabilities Assets, Current Total current assets Excess of accrued right to purchase stock Excess of accrued right to purchase stock Accrued expenses and other current liabilities disclosure. Accrued Expenses And Other Current Liabilities Disclosure [Text Block] ACCRUED EXPENSES AND OTHER LIABILITIES Realized gains and losses on available-for-sale securities Debt Securities, Available-for-sale, Realized Gain (Loss) Debt Securities, Available-for-sale, Realized Gain (Loss), Total Equity method investment cash consideration Equity method investment Equity Method Investment, Aggregate Cost Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Weighted Average Remaining Contractual Term, Outstanding Income tax provision Income tax provision Provision for income taxes Income Tax Expense (Benefit) Income Tax Expense (Benefit), Total Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Supplemental disclosures of noncash investing and financing activities: Accrued unvested common stock subject to repurchase current. Accrued Unvested Common Stock Subject to Repurchase Current Liability for unvested common shares subject to repurchase included in accrued expenses and other liabilities Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested Options Forfeited, Weighted Average Grant Date Fair Value Weighted-Average Grant Date Fair Value, Forfeited Antidilutive Securities [Axis] Antidilutive Securities Consolidation, Policy [Policy Text Block] Principles of Consolidation Bedford, Massachusetts. Bedford Massachusetts [Member] Bedford, Massachusetts Security Deposit Liability Security deposit Reimbursable research and development costs. Reimbursable Research And Development Costs [Member] Reimbursable Research and Development Costs Dilutive securities Dilutive Securities, Effect on Basic Earnings Per Share Dilutive Securities, Effect on Basic Earnings Per Share, Total Aggregate Intrinsic Value, Vested and Expected to vest at March 31, 2022 Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Commission fee Commission Fee Commission Fee Common Stock, Shares, Outstanding Common stock, shares outstanding Common Stock, Shares, Outstanding, Beginning Balance Common Stock, Shares, Outstanding, Ending Balance Plan Name [Axis] Plan Name Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Less: accumulated depreciation and amortization RSU, Forfeited Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Collaborative Arrangement and Arrangement Other than Collaborative [Table] Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table] Sale of Stock, Consideration Received on Transaction Net proceeds after deducting underwriting discounts and commissions and offering expenses Revenue [Policy Text Block] Revenue Recognition Accrued income taxes Accrued Income Taxes Accrued Income Taxes, Total Operating Expenses Total operating expenses IPO [Member] Initial Public Offering Lease Amendment Lease, Cost Net lease cost Debt Securities, Available-for-sale, Accumulated Gross Unrealized Loss, before Tax Cash equivalents and short-term investments, Unrealized Losses Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Weighted-Average Exercise Price per Share, Outstanding at Ending Balance Weighted-Average Exercise Price per Share, Outstanding at Beginning Balance Net Cash Provided by (Used in) Operating Activities [Abstract] Cash flows from operating activities: Common stock estimated fair value. Common Stock Estimated Fair Value Common stock estimated fair value Lessee, Operating Lease, Liability, Maturity [Table Text Block] Schedule of Operating Lease Liabilities and Minimum Lease Payments Net income (loss) per share-diluted Net income (loss) per share-diluted Earnings Per Share, Diluted Debt Securities, Available-for-sale, Accumulated Gross Unrealized Gain, before Tax Cash equivalents and short-term investments, Unrealized Gains Earnings Per Share [Abstract] Schedule of lease term and discount rate table text block. Schedule Of Lease Term And Discount Rate Table [Text Block] Schedule of Lease Term and Discount Rate 2024 Lessee, Operating Lease, Liability, to be Paid, Year Two Net income (loss) Net income (loss) Net income Net Income (Loss) Attributable to Parent Net loss Compensation and Employee Benefit Plans [Text Block] STOCK INCENTIVE PLANS Operating Lease, Weighted Average Discount Rate, Percent Weighted-average discount rate, Operating leases Research and Development Expense [Member] Research and Development Document Fiscal Period Focus Document Fiscal Period Focus Annual Base Rent Per Year For Premise Annual base rent per year for premise. Annual base rent per year Accounting Policies [Abstract] Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive loss Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Entity Address, Address Line One Entity Address, Address Line One Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value Total intrinsic value of options exercised Number of Options, Outstanding at Beginning Balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Number of Options, Outstanding at Ending Balance Liabilities, Current Total current liabilities Net income (loss) Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Commercial Paper [Member] Commercial Paper Entity Address, Postal Zip Code Entity Address, Postal Zip Code Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Weighted-average risk-free interest rate, maximum Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value Aggregate Intrinsic Value, Outstanding Ending Balance Lessee, Operating Lease, Liability, to be Paid Total undiscounted lease payments Subsequent Event [Table] Pfizer Inc. Pfizer Inc [Member] Pfizer Inc. Proceeds from Sale of Debt Securities, Available-for-sale Maturities of short-term investments Proceeds from Issuance Initial Public Offering Net proceeds from initial public offering after underwriting discounts and commissions and offering expenses Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized Number of additional shares added to the plan Equipment [Member] Manufacturing Equipment Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Collaborative Arrangement and Arrangement Other than Collaborative Net Cash Provided by (Used in) Operating Activities Net cash used in operating activities Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations Cash, cash equivalents and restricted cash, end of period Cash, cash equivalents and restricted cash, beginning of period Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total Equity Components [Axis] Equity Components Lease, Cost [Table Text Block] Schedule of Operating Lease Costs, Variable Lease Costs and Sub Lease Income Assets, Current [Abstract] Current assets: Variable Lease, Cost Variable lease costs Commitment and contingencies. Commitment And Contingencies [Line Items] Commitment And Contingencies [Line Items] Entity Registrant Name Entity Registrant Name The entire disclosure for stock purchase agreement. Stock Purchase Agreement Disclosure [Text Block] PFIZER STOCK PURCHASE AGREEMENT Gain (Loss) on Disposition of Property Plant Equipment Loss on disposal of property and equipment Gain (Loss) on Disposition of Property Plant Equipment, Total Entity Interactive Data Current Entity Interactive Data Current Unvested common shares subject to repurchase outstanding. Unvested Common Shares Subject To Repurchase Outstanding Unvested shares, Ending Balance Unvested shares, Beginning Balance Remaining shares subject to repurchase Entity Address, City or Town Entity Address, City or Town Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum Expected volatility, minimum Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Expected term (in years) Option to extend sublease Lessee, Operating Sublease, Option to Extend Trading Symbol Trading Symbol RELATED PARTY TRANSACTIONS Related Party Transactions Disclosure [Text Block] Net Cash Provided by (Used in) Investing Activities [Abstract] Cash flows from investing activities: Lessee, Operating Lease, Liability, Undiscounted Excess Amount Less: imputed interest Accrued expenses and other liabilities member. Accrued Expenses and Other Liabilities [Member] Accrued Expenses and Other Liabilities Local Phone Number Local Phone Number Sale of Stock, Percentage of Ownership after Transaction Sale of Stock, Percentage of Ownership after Transaction Stockholders' Equity Attributable to Parent Ending balance Beginning balance Total stockholders’ equity Comprehensive Income, Policy [Policy Text Block] Comprehensive Income (Loss) Preferred Stock, Shares Issued Preferred stock, shares issued Preferred Stock, Shares Issued, Total Assets, Fair Value Disclosure Financial assets, fair value Financial assets, fair value Statistical Measurement [Axis] Statistical Measurement Entity Small Business Entity Small Business Payments to Acquire Debt Securities, Available-for-sale Purchases of short-term investments Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Preferred Stock, Shares Outstanding, Beginning Balance Preferred Stock, Shares Outstanding, Ending Balance Organization, Consolidation and Presentation of Financial Statements [Abstract] Lessee, Leases [Policy Text Block] Leases Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period Number of Options, Cancelled/Forfeited Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period, Total Share Price Common stock at a public offering price Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV Compensation cost, Total Deferred Compensation Liability, Current Deferred Compensation Liability, Current, Total Credit Facility [Axis] Credit Facility Entity [Domain] Less: Carrying value of transferred assets Carrying Value of the Transferred Asset Carrying Value of the Transferred Asset Balance Sheet Location [Axis] Balance Sheet Location Recorded purchases Related Party Transaction, Amounts of Transaction Deferred Charges, Policy [Policy Text Block] Offering Costs Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Weighted-Average Exercise Price per Share, Granted Sale of Stock [Domain] Sale of Stock Equity [Abstract] Related Party Transaction [Line Items] Related Party Transaction [Line Items] Plan Name [Domain] Plan Name Other comprehensive gain (loss) Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Total other comprehensive loss Depreciation Depreciation Depreciation, Total Purchase Commitment Amount Long-term Purchase Commitment, Amount Partners' Capital Account, Sale of Units Partners' Capital Account, Sale of Units Partners' Capital Account, Sale of Units, Total Stock Issued During Period, Value, New Issues Issuance of common stock, net of discounts and issuance costs Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis] Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date Common stock offering expenses Common Stock Offering Expenses Common stock offering expenses Major asset class of leased assets [Domain]. Major Asset Class Of Leased Assets [Domain] Major Asset Class Of Leased Assets Property, Plant and Equipment, Disposals Disposal of property and equipment Share-based Payment Arrangement, Noncash Expense Stock-based compensation expense Share-based Payment Arrangement, Noncash Expense, Total Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Amount of lessee's undiscounted obligation for lease payment for operating lease due after third fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach). Lessee Operating Lease Liability Payments Due After Year Three Thereafter Share-based Payment Arrangement, Option, Activity [Table Text Block] Summary of Option Activity under Plans Long-Lived Tangible Asset [Domain] Long-Lived Tangible Asset Related Party Transactions [Abstract] Lessor, Operating Lease, Term of Contract Lease Term Proceeds from future issuance stock. Proceeds From Future Issuance Stock Proceeds through future financings Increase in lease liabilities and right-of-use assets due to lease remeasurement Lease Remeasurement Increase In Lease Liability And Right Of Use Assets Lease remeasurement Increase In Lease liability And right of use assets. Stock issued during period value vesting of common stock from option exercise. Stock Issued During Period Value Vesting Of Common Stock From Option Exercise Vesting of common stock from option exercises Number of Options, Exercisable at March 31, 2022 Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Net Cash Provided by (Used in) Financing Activities Net cash provided by financing activities Commitments and Contingencies Disclosure [Abstract] Assets Total assets Fair Value, Inputs, Level 2 [Member] Significant Other Observable Inputs (Level 2) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Issuance of common stock from option exercises, Shares Number of Options, Exercised Additional units issued Limited Partners' Capital Account, Units Issued Statement [Line Items] Statement [Line Items] Liabilities and Equity Total liabilities and stockholders' equity Document Quarterly Report Document Quarterly Report Balance Sheet Location [Domain] Balance Sheet Location Property, Plant and Equipment [Abstract] Statement of Cash Flows [Abstract] Novartis Institutes of BioMedical Research, Inc. Novartis Institutes Of Bio Medical Research Inc [Member] Novartis Additional Paid-in Capital [Member] Additional Paid-in Capital Title of 12(b) Security Title of 12(b) Security Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive loss Percentage increase in initial annual base rent Lessee operating lease not yet commenced increase in percentage of base rent. Lessee Operating Lease Not Yet Commenced Increase In Percentage Of Base Rent Percentage increase in initial annual base rent per square foot. Share based compensation arrangement by share based payment award purchase price of common stock through payroll deductions percentage. Share Based Compensation Arrangement By Share Based Payment Award Purchase Price Of Common Stock Through Payroll Deductions Percentage Purchase of common stock through payroll deductions expressed in percentage of fair market value Fair Value, Inputs, Level 3 [Member] Significant Unobservable Inputs (Level 3) Award Type [Domain] Award Type Share-based Goods and Nonemployee Services Transaction, Modification of Terms, Incremental Compensation Cost Fair Value Hierarchy and NAV [Axis] Significant Unobservable Inputs (Level 3) Collaborative Arrangement [Member] Collaborative Arrangement Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period Stock options expiration period Property, Plant and Equipment [Table Text Block] Schedule of Property and Equipment, Net Fair Value, Inputs, Level 1 [Member] Quoted Prices (Unadjusted) in Active Markets for Identical Assets (Level 1) Gain on sale of equity method investment Gain (Loss) On Sale Of Equity Method Investment [Table Text Block] Gain (Loss) On Sale Of Equity Method Investment [Table Text Block] Lease beginning date year and month. Lease Beginning Date Year And Month Operating lease beginning year and month Area of Real Estate Property Office space leased Corporate Debt Securities [Member] Corporate Debt Securities Weighted-Average Exercise Price per Share, Vested and Expected to vest at March 31, 2022 Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Number of Options, Granted Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Entity Current Reporting Status Entity Current Reporting Status Collaborative Arrangement Disclosure [Text Block] COLLABORATION AND LICENSE AGREEMENT Investment Type [Axis] Investment Type Revenue, Remaining Performance Obligation, Amount Remaining performance obligation, unsatisfied portion Allocated Information Committee obligation Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Weighted-average risk-free interest rate, minimum Scenario [Domain] Increase decrease in operating lease liabilities. Increase Decrease In Operating Lease Liabilities Operating lease liabilities Fair value of the equity method investment Equity Method Investment, Quoted Market Value Money Market Funds [Member] Money Market Mutual Funds Stock issued during period shares vesting of common stock from option exercise. Stock Issued During Period Shares Vesting Of Common Stock From Option Exercise Vesting of common stock from option exercises, Shares Earnings Per Share, Policy [Policy Text Block] Net Loss per Share 2022 Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Computer Equipment [Member] Computers and Purchased Software Lessee, Operating Lease, Lease Not yet Commenced, Renewal Term Lessee, operating lease, lease not yet commenced, renewal term Oxford Biomedica Plc Member Oxford Biomedica plc [Member] Oxford Biomedica plc [Member] Number of phases. Number Of Phases Number of phases Loss from equity method investment Loss on equity method investment Equity Method Investment, Realized Gain (Loss) on Disposal Equity Method Investment, Realized Gain (Loss) on Disposal, Total AOCI Attributable to Parent [Member] Accumulated Other Comprehensive Gain (Loss) Income Statement Location [Domain] Income Statement Location Repurchase Agreements [Member] Repurchase Agreements 2018 Employee Stock Purchase Plan. Twenty Eighteen Employee Stock Purchase Plan [Member] 2018 Employee Stock Purchase Plan Office Equipment [Member] Laboratory Equipment Net income (loss) per share-basic Earnings Per Share, Basic Earnings Per Share, Basic, Total Preferred Stock, Shares Authorized Preferred stock, shares authorized Weighted-Average Exercise Price Per Share, Exercisable at March 31, 2022 Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Organization consolidation and presentation of financial statements disclosure. Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] Underwriters option. Underwriters Option [Member] Underwriters Option Minimum Minimum [Member] Minimum Weighted Average Remaining Contractual Term, Vested and Expected to vest at March 31, 2022 Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Measurement Frequency [Domain] Measurement Frequency Stock Issued During Period, Value, Stock Options Exercised Issuance of common stock from option exercises Lease Amendment Lease Amendment [Member] Lease amendment. Reclassification of liability for common stock vested in noncash transactions. Reclassification Of Liability For Common Stock Vested In Noncash Transactions Reclassification of liability for common stock vested Equity method investment, lack of control percentage Equity Method Investment Lack Of Control Percentage Equity Method Investment Lack Of Control Percentage Schedule of equity method investment fair value Equity Method Investments [Table Text Block] Rent start date year and month. Rent Start Date Year And Month Rent due date Oxford Biomedica Oxford Biomedica [Member] Oxford biomedica member. Plus: Fair value of equity method investment Fair value of equity method investment Fair value of equity method investment Schedule of operating lease liabilities table text block. Schedule Of Operating Lease Liabilities Table [Text Block] Schedule of Operating Lease Liabilities Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows from financing activities: Entity Filer Category Entity Filer Category Income Taxes Income Tax, Policy [Policy Text Block] Document Fiscal Year Focus Document Fiscal Year Focus Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Number of Options, Vested and expected to vest at March 31, 2022 Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Equity Method Investment Equity Method Investments [Policy Text Block] Cash received Proceeds from Sale of Equity Method Investments Proceeds from Sale of Equity Method Investments Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Weighted-average grant date fair value per share for options granted Retained Earnings (Accumulated Deficit) Accumulated deficit Accumulated deficit Retained Earnings (Accumulated Deficit), Total Retained Earnings (Accumulated Deficit), Beginning Balance Retained Earnings (Accumulated Deficit), Ending Balance Units issued in exchange for transferred assets Common Unit, Issued Cash, cash equivalents, and available-for-sale securities. Cash Cash Equivalents And Available For Sale Securities [Abstract] Entity Ex Transition Period Entity Ex Transition Period Clinical supply requirements Roadrunner Solutions LLC Fully Diluted Equity Interests Roadrunner solutions LLC fully diluted equity interests. Fair Value Disclosures [Abstract] Letters of credit and secured by restricted cash. Letters Of Credit And Secured By Restricted Cash [Member] Letters Of Credit And Secured By Restricted Cash Property, Plant and Equipment Disclosure [Text Block] PROPERTY AND EQUIPMENT, NET Maximum Maximum [Member] Entity Central Index Key Entity Central Index Key Share based compensation arrangement by share based payment award stock offering period. Share Based Compensation Arrangement By Share Based Payment Award Stock Offering Period Common stock offering period Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents and Restricted Cash Interest income Interest income Interest income Payables and Accruals [Abstract] Cash, Cash Equivalents, and Short-term Investments [Text Block] SHORT-TERM INVESTMENTS Schedule of cash, cash equivalents and available-for-sale securities. Schedule Of Cash Cash Equivalents And Available For Sale Securities [Line Items] Schedule Of Cash Cash Equivalents And Available For Sale Securities [Line Items] Entity Tax Identification Number Entity Tax Identification Number Equity Component [Domain] Equity Component Preferred Stock, Par or Stated Value Per Share Preferred stock, par value Commitment and contingencies. Commitment And Contingencies [Table] Commitment And Contingencies [Table] Investments disclosure. Investments Disclosure [Abstract] Phase two. Phase Two [Member] Phase Two Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Unrecognized compensation expense estimated to be recognized over period Subsequent Events [Abstract] Subsequent Event [Line Items] Leasehold Improvements [Member] Leasehold Improvements Homology Homology Member Homology [Member] Homology [Member] Increase (Decrease) in right-of-use asset Increase (Decrease) in right-of-use asset Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized Number of shares available for issuance Statement [Table] Statement [Table] Operating Lease, Weighted Average Remaining Lease Term Weighted-average remaining lease term (years), Operating leases Entity File Number Entity File Number Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Accrued expenses and other liabilities current. Accrued Expenses And Other Liabilities Current Accrued expenses and other liabilities Total accrued expenses and other liabilities Retained Earnings [Member] Accumulated Deficit Shares Issued, Price Per Share Shares issued price per share Revenue from Contract with Customer, Excluding Assessed Tax Collaboration revenue Collaboration agreement revenue recognized Revenue from Contract with Customer, Excluding Assessed Tax, Total Payments of Stock Issuance Costs Payments Of Stock Issuance Costs Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Accounts Payable, Total Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] 2018 Incentive Award Plan. Two Thousand Eighteen Incentive Award Plan [Member] 2018 Incentive Award Plan Tenant improvements allowance. Tenant Improvements Allowance Tenant improvement allowance Liabilities, Current [Abstract] Current liabilities: Commitments and Contingencies Disclosure [Text Block] COMMITMENTS AND CONTINGENCIES Operating Lease, Liability Present value of operating lease liabilities Operating Lease, Liability, Total Common Stock [Member] Common Stock Property, Plant and Equipment, Gross Property and equipment, at cost Property, Plant and Equipment, Gross, Total Property, Plant and Equipment, Gross, Beginning Balance Property, Plant and Equipment, Gross, Ending Balance Accrued Professional Fees, Current Accrued professional fees Cover [Abstract] Credit Facility [Domain] Credit Facility Restrictions on Cash and Cash Equivalents [Table Text Block] Reconciliation of Cash, Cash Equivalents and Restricted Cash OXB OXB [Member] OXB [Member] Statement of Stockholders' Equity [Abstract] Property, Plant and Equipment [Table] Schedule Of Property Plant And Equipment [Table] Fair value of investment Investment Owned, at Fair Value Share-based Payment Arrangement [Abstract] RSU Member Restricted Stock Units (RSUs) [Member] Long-Lived Tangible Asset [Axis] Long-Lived Tangible Asset Other Accrued Liabilities, Current Accrued other Document Transition Report Document Transition Report Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Weighted Average Grant Date Fair Value Weighted-Average Grant Date Fair Value, Vested Proceeds from Stock Options Exercised Proceeds from issuance of common stock from option exercises Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price Weighted-Average Exercise Price per Share, Cancelled/Forfeited Lessee, Operating Lease, Renewal Term Operating lease agreements additional term Share-based Payment Arrangement, Noncash Expense [Abstract] Number of Options, Exercised Share Based Compensation Arrangement By Share Based Payment Award Options Exercised In Period Gross Share based compensation arrangement by share based payment award options exercised in period gross. Accrued research and development expenses current. Accrued Research And Development Expenses Current Accrued research and development expenses Research and Development Expense Research and development Research and Development Expense, Total Fair value assets (liabilities) transfer between levels. Fair Value Assets Liabilities Transfer Between Levels Transfers between fair value measure levels Deferred revenue, net of current portion Contract with Customer, Liability, Noncurrent Weighted-average common shares outstanding-diluted Weighted Average Number of Shares Outstanding, Diluted Weighted Average Number of Shares Outstanding, Diluted, Total Share-based Payment Arrangement, Expense Stock-based compensation Statement of Financial Position [Abstract] Unvested common shares subject to repurchase issued. Unvested Common Shares Subject To Repurchase Issued Issued Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend yield RSU Vested RSU Vested Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period Lease Contractual Term [Axis] Lease Contractual Term Assets held for sale Assets Held-for-sale, Not Part of Disposal Group Assets Held-for-sale, Not Part of Disposal Group, Total APIC, Share-based Payment Arrangement, Option, Increase for Cost Recognition Stock-based compensation Stockholders' Equity Attributable to Parent [Abstract] Stockholders’ equity: Lease Contractual Term [Domain] Lease Contractual Term Equity method valuation assumptions marketability Equity method valuation assumptions marketability Share-based Compensation Arrangement by Share-based Payment Award, Option, Nonvested, Weighted Average Exercise Price Weighted-Average Grant Date Fair Value, Outstanding Weighted-Average Grant Date Fair Value, Outstanding Total compensation cost reversed Total compensation cost reversed Share-based Compensation Arrangements by Share-based Payment Award, Restricted Stock Units, Vested and Expected to Vest [Table Text Block] Summary of Company's RSU Activity EQUITY METHOD INVESTMENT Equity Method Investments and Joint Ventures Disclosure [Text Block] Carrying value of the equity method investment Equity Method Investments Summary of unvested common stock from early exercises subject to repurchase. Summary Of Unvested Common Stock From Early Exercises Subject To Repurchase Table [Text Block] Summary of Unvested Common Stock from Early Exercises Subject to Repurchase Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Weighted-Average Exercise Price per Share, Exercised Non cash lease expense. Non Cash Lease Expense Noncash lease expense Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: 2025 Lessee, Operating Lease, Liability, to be Paid, Year Three Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Common Stock, Capital Shares Reserved for Future Issuance Number of additional shares available for future grant Major asset class of leased assets [Axis]. Major Asset Class Of Leased Assets [Axis] Major Asset Class Of Leased Assets Measurement Frequency [Axis] Measurement Frequency Award Type [Axis] Award Type Entity Shell Company Entity Shell Company Other comprehensive loss: Other Comprehensive Income (Loss), Net of Tax [Abstract] Liabilities and Equity [Abstract] Liabilities and stockholders' equity Annual base rent Annual Base Rent For Premise Annual base rent for premise. Transferred units Partners' Capital Account, Units, Sale of Units Partners' Capital Account, Units, Sale of Units, Total Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Stock Issued During Period, Value, Employee Stock Purchase Plan Issuance of common stock pursuant to employee stock purchase plan NET INCOME (LOSS) PER SHARE Earnings Per Share [Text Block] Counterparty Name [Domain] Counterparty Name Liabilities, Noncurrent [Abstract] Non-current liabilities: Amendment Flag Amendment Flag Other Nonoperating Income (Expense) Total other income Increase (Decrease) in Contract with Customer, Liability Deferred revenue Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value, Total Cash and Cash Equivalents, at Carrying Value, Beginning Balance Cash and Cash Equivalents, at Carrying Value, Ending Balance Expenses recognized under the transitional services Selling Expense New Accounting Pronouncements, Policy [Policy Text Block] Recent Accounting Pronouncements Less: Estimated lease incentives Amortization of Lease Incentives Initial base rent per square feet. Initial Base Rent Per Square Feet Initial annual base rent per square foot Ownership interests, units Other Ownership Interests, Units Outstanding Fair Value, Recurring [Member] Fair Value, Measurements, Recurring SUBSEQUENT EVENTS Subsequent Events [Text Block] Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities Accrued expenses and other liabilities Equity method investments, ownership description Equity Method Investment, Material Effects of Possible Conversions, Exercises or Contingent Issuances Unvested common shares subject to repurchase vested. Unvested Common Shares Subject To Repurchase Vested Vested ATM Member A T M [Member] A T M Antidilutive Securities, Name [Domain] Antidilutive Securities, Name Property, Plant and Equipment [Line Items] Property Plant And Equipment [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Collaborative Arrangement and Arrangement Other than Collaborative Geographical [Domain] Geographical Aggregate Intrinsic Value, Exercisable at March 31, 2022 Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value Sale of Stock [Axis] Sale of Stock Two thousand fifteen stock incentive plan. Two Thousand Fifteen Stock Incentive Plan [Member] 2015 Stock Incentive Plan Share-based Payment Arrangement, Cost by Plan [Table Text Block] Schedule of Stock-Based Compensation Expense Two thousand fifteen and two thousand eighteen stock incentive plans. Two Thousand Fifteen And Two Thousand Eighteen Stock Incentive Plans [Member] 2015 and 2018 Stock Incentive Plans Fair Value Disclosures [Text Block] FAIR VALUE MEASUREMENTS Share-based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount Unrecognized compensation expense Proceeds from issuance of common stock pursuant to ATM, net of discounts and issuance costs Proceeds from Issuance of Common Stock Net proceed from issuance of common stock