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Income Taxes - Schedule of Reconciliation between U.S. Federal Statutory Tax Rate and Effective Tax Rate (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
Federal statutory rate 21.00% 21.00%
Tax credits 9.30% 10.60%
State taxes, net of federal tax benefit 8.60% 8.00%
Non-deductible expenses (1.40%) (1.80%)
Other 2.60%
Change in valuation allowance (40.10%) (37.80%)
Effective income tax rate 0.00% 0.00%