Property and Equipment - Schedule of Property and Equipment, Net (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Property Plant And Equipment [Line Items]
Property and equipment, at cost	$ 8,098	$ 53,377
Less accumulated depreciation and amortization	(5,846)	(16,375)
Property and equipment, net	2,252	37,002
Laboratory Equipment
Property Plant And Equipment [Line Items]
Property and equipment, at cost	5,857	12,703
Manufacturing Equipment
Property Plant And Equipment [Line Items]
Property and equipment, at cost		7,754
Computers and Purchased Software
Property Plant And Equipment [Line Items]
Property and equipment, at cost	1,596	1,596
Furniture and Fixtures
Property Plant And Equipment [Line Items]
Property and equipment, at cost	645	1,363
Leasehold Improvements
Property Plant And Equipment [Line Items]
Property and equipment, at cost		$ 29,961