Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2021

Accounting Policies [Abstract]

Reconciliation of Cash, Cash Equivalents and Restricted Cash

The following table provides a reconciliation of cash, cash equivalents and restricted cash to amounts shown in the consolidated statements of cash flows:

	December 31,
	2021		2020
	(in thousands)
Cash and cash equivalents	$	108,382	$	217,431
Restricted cash		1,953		1,274
Total cash, cash equivalents and restricted cash	$	110,335	$	218,705

Impact of Adoption of Previously Reported Amounts of Financial Statement

	January 1, 2020 (in thousands)
	Prior to adoption of new leasing standards		Adjustment for adoption of new leasing standards			As Adjusted
Right-of-use assets (1)(2)	$	—	$	6,835		$	6,835
Deferred rent (2)	$	1,313	$	(1,313	)	$	—
Deferred rent, net of current portion (2)	$	9,544	$	(9,544	)	$	—
Operating lease liabilities (3)	$	—	$	2,251		$	2,251
Operating lease liabilities, net of current portion (3)	$	—	$	15,441		$	15,441
(1) Represents capitalization of operating right-of-use assets
(2) Represents reclassification of deferred rent and incentives as a reduction to operating right-of-use assets
(3) Represents recognition of operating lease liabilities

Schedule of Estimated Useful Life of Asset

Computer equipment and software	3 years
Laboratory equipment and office furniture	5 years
Manufacturing equipment	5 - 7 years
Leasehold improvements	Shorter of the lease term or estimated useful life