X0206 3 2018-04-18 0 0001718108 Surface Oncology, Inc. SURF 0001661908 Sigal Charles Elliott C/O SURFACE ONCOLOGY, INC. 50 HAMPSHIRE STREET, 8TH FLOOR CAMBRIDGE MA 02139 1 0 0 0 Stock Option (Right to Buy) 0.36 2025-05-14 Common Stock 113636 D Stock Option (Right to Buy) 9.62 2028-02-05 Common Stock 58409 D Series A Preferred Stock Common Stock 45453 I See Footnote The stock option vested and became exercisable in 36 equal monthly installments after December 1, 2014. The stock option vests and becomes exercisable in 36 equal monthly installments after February 5, 2018. The Series A Preferred Stock is convertible on a 2.2-for-1 basis into Common Stock at any time at the election of the holder and will automatically convert upon the closing of the Issuer's initial public offering into the number of shares of the Issuer's Common Stock shown in column 3 without payment or further consideration. The shares have no expiration date. The shares are held by Sigal Family Investments, LLC. The Reporting Person may be deemed to have voting and dispositive power with respect to the shares held by Sigal Family Investments, LLC. The Reporting Person disclaims beneficial ownership of such shares except to the extent of any pecuniary interest therein. Exhibit 24.1 Limited Power of Attorney /s/ Charles Elliott Sigal 2018-04-18