X0306 4 2016-08-11 0 0001621227 Adaptimmune Therapeutics PLC ADAP 0001661908 Sigal Charles Elliott 32 BREARLY ROAD PRINCETON NJ 08540 1 0 0 0 Option to purchase Ordinary Shares 1.27 2016-08-11 4 A 0 184562 0 A 2017-08-11 2026-08-11 Ordinary Shares 184562 184562 D The exercise price was converted from GBP0.97 based on the closing midpoint exchange rate for the U.S. dollar on the day prior to the date of grant listed in the Financial Times. The actual exercise price will be the pounds sterling amount. /s/ Charles Elliott Sigal 2016-08-12