Restructuring - Additional Information (Detail) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Mar. 09, 2022 USD ($) Employees	Dec. 31, 2021 USD ($)	Oct. 21, 2020 Employees
Restructuring Cost and Reserve [Line Items]
Restructuring Charges	$ 643	$ 939	$ 907	$ 1,866
Restructuring Reserve Current	661		661			$ 3,168
Birmingham Restructuring
Restructuring Cost and Reserve [Line Items]
Restructuring and Related Cost					$ 3,000
Number of employees to retention Benefits | Employees					25
Employee Cost
Restructuring Cost and Reserve [Line Items]
Restructuring Charges	523		638
Employee Cost | Birmingham Restructuring
Restructuring Cost and Reserve [Line Items]
Restructuring and Related Cost					$ 2,000
Facility and Other
Restructuring Cost and Reserve [Line Items]
Restructuring Charges	$ 120		$ 269
Facility and Other | Birmingham Restructuring
Restructuring Cost and Reserve [Line Items]
Restructuring and Related Cost					$ 1,000
La Jolla Restructuring
Restructuring Cost and Reserve [Line Items]
Number of employees to retention Benefits | Employees							65