X0306 4 2017-05-11 0 0001660719 Aralez Pharmaceuticals Inc. ARLZ 0001258673 KOVEN ANDREW I C/O ARALEZ PHARMACEUTICALS INC., 7100 WEST CREDIT AVENUE, SUITE 101 MISSISSAUGA A6 L5N 0E4 ONTARIO, CANADA 0 1 0 0 President & CBO Common Shares, without par value 2017-05-11 4 A 0 109190 0 A 1525601 D Employee Stock Option (right to buy) 1.56 2017-05-11 4 A 0 126158 0 A 2027-05-11 Common Shares, without par value 126158 126158 D Restricted Stock Units granted pursuant to the Aralez Pharmaceuticals Inc. 2016 Amended and Restated Long-Term Incentive Plan, which vest in substantially equal annual installments over the three years immediately following the date of grant, subject to continued employment or service to the Company. Includes 267,483 shares of Common Stock and 1,258,118 Restricted Stock Units. The option vests as to 25% of the shares on May 11, 2018, and the remainder vests in substantially equal monthly installments over the 36 months immediately following such date, subject to continued employment or service to the Company. /s/ Eric L. Trachtenberg, attorney-in-fact for Andrew I. Koven 2017-05-12