<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2018-10-30-06:00</periodOfReport>

    <notSubjectToSection16>false</notSubjectToSection16>

    <issuer>
        <issuerCik>0001474167</issuerCik>
        <issuerName>Cosmos Holdings Inc.</issuerName>
        <issuerTradingSymbol>COSM</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001660125</rptOwnerCik>
            <rptOwnerName>Siokas Grigorios</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>5 AG. GEORGIOU STR., PILEA</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>THESSALONIKI</rptOwnerCity>
            <rptOwnerState>J3</rptOwnerState>
            <rptOwnerZipCode>TK57001</rptOwnerZipCode>
            <rptOwnerStateDescription>GREECE</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
            <isOfficer>true</isOfficer>
            <isTenPercentOwner>true</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle>Chief Executive Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

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                <equitySwapInvolved>false</equitySwapInvolved>
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            <transactionAmounts>
                <transactionShares>
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                </transactionShares>
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                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
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                <equitySwapInvolved>false</equitySwapInvolved>
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                <transactionShares>
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                </transactionShares>
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                <transactionAcquiredDisposedCode>
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                <equitySwapInvolved>false</equitySwapInvolved>
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                <transactionAcquiredDisposedCode>
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    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Grigorios Siokas</signatureName>
        <signatureDate>2018-11-01-06:00</signatureDate>
    </ownerSignature>
</ownershipDocument>
