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Note 7 - Commitments and Contingencies (Details Textual) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Operating Lease, Monthly Rent Payment $ 4,700        
Operating Lease, Rent Expense, Annual Increase In Rent, Percent 2.00%        
Sublease Income   $ 12,000 $ 12,000 $ 37,000 $ 37,000
Operating Lease, Payments   40,000 39,000 119,000 107,000
Research and Development Expense   3,738,000 4,932,000 10,774,000 13,274,000
Houston Pharmaceuticals, Inc [Member]          
Costs and Expenses, Related Party   15,000 15,000 45,000 176,000
MD Anderson [Member]          
License Agreements Expense   32,000 63,000 115,000 180,000
Research and Development Expense   $ 11,000 $ 767,000 $ 324,000 $ 1,300,000