Note 5 - Warrants - Warrants Outstanding (Details) - $ / shares		12 Months Ended
		Dec. 31, 2024	Dec. 31, 2023	Aug. 31, 2024	Aug. 31, 2023	Jun. 30, 2023
Balance outstanding (in shares)		7,810,033	1,372,172
Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 2.8
Warrants Issued in March 2019 [Member]
Balance outstanding (in shares)	[1]	0	17,573
Warrants Issued in April 2019 [Member]
Balance outstanding (in shares)	[1]	0	58,336
Warrants Issued in February 2020 [Member]
Balance outstanding (in shares)	[1]	67,670	67,670
Warrants Issued in February 2020 [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)	[1]	$ 94.5
Warrants Issued in December 2023 [Member]
Balance outstanding (in shares)	[1]	939,316	939,316
Balance outstanding, remaining contractual life (Year)	[1]	4 years 9 months 18 days
Warrants Issued in December 2023 [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)	[1]	$ 2.57
Warrants Issued in August 2024 [Member]
Balance outstanding (in shares)	[1]	5,056,054	0
Balance outstanding, remaining contractual life (Year)	[1]	3 years 4 months 24 days
Warrants Issued in August 2024 [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)	[1]	$ 2.24
Liability Classified Warrants [Member]
Balance outstanding (in shares)		6,063,040	1,082,895
Balance outstanding, remaining contractual life (Year)		3 years 6 months	5 years 1 month 6 days
Liability Classified Warrants [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 3.32	$ 24.32
Warrants Issued in April 2020 for Consulting [Member]
Balance outstanding (in shares)		0	1,112
Warrants Issued in April 2020 for Consulting [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 0
Warrants Issued in December 2020 for Consulting [Member]
Balance outstanding (in shares)		556	556
Balance outstanding, remaining contractual life (Year)		1 year
Warrants Issued in December 2020 for Consulting [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 70.8
Warrant Issued in April 2021 for Consulting [Member]
Balance outstanding (in shares)		4,767	4,767
Balance outstanding, remaining contractual life (Year)		1 year 3 months 18 days
Warrant Issued in April 2021 for Consulting [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 54.45
Warrant Issued in August 2021 for Consulting [Member]
Balance outstanding (in shares)		16,667	16,667
Balance outstanding, remaining contractual life (Year)		6 years 7 months 6 days
Warrant Issued in August 2021 for Consulting [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 46.2
Warrants Issued in June 2022 for Consulting [Member]
Balance outstanding (in shares)		3,334	3,334
Balance outstanding, remaining contractual life (Year)		7 years 6 months
Warrants Issued in June 2022 for Consulting [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 22.35
Warrant Issued in September 2022 for Consulting [Member]
Balance outstanding (in shares)		16,667	16,667
Balance outstanding, remaining contractual life (Year)		7 years 8 months 12 days
Warrant Issued in September 2022 for Consulting [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 18.6
Warrants Issued in June 2023 for Consulting [Member]
Balance outstanding (in shares)		10,001	10,001
Balance outstanding, remaining contractual life (Year)		8 years 6 months
Warrants Issued in June 2023 for Consulting [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 9
Warrants Issued in August 2023 for Consulting [Member]
Balance outstanding (in shares)		6,667	6,667
Balance outstanding, remaining contractual life (Year)		3 years 7 months 6 days
Warrants Issued in August 2023 for Consulting [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 9.3
Pre-funded Warrants Member Issued In Connection With The 2023 Securities Purchase Agreement[Member]
Balance outstanding (in shares)		0	229,506
Balance outstanding, warrant exercise price (in dollars per share)		$ 0.001
Warrants Issued in March 2024 for Consulting [Member]
Balance outstanding (in shares)		3,334	0
Balance outstanding, remaining contractual life (Year)		9 years 2 months 12 days
Warrants Issued in March 2024 for Consulting [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 9.15
Pre-funded Warrants in 2024 Agreement [Member]
Balance outstanding (in shares)		1,649,000	0
Balance outstanding, warrant exercise price (in dollars per share)				$ 0.001
Pre-funded Warrants in 2024 Agreement [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 0.001
Warrants Issued in October 2024 for Consulting [Member]
Balance outstanding (in shares)		36,000	0
Balance outstanding, remaining contractual life (Year)		9 years 9 months 18 days
Warrants Issued in October 2024 for Consulting [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 2.36
Equity Classified Warrants [Member]
Balance outstanding (in shares)		1,746,993	289,277
Balance outstanding, warrant exercise price (in dollars per share)					$ 9.3	$ 9
Equity Classified Warrants [Member] | Weighted Average [Member]
Balance outstanding, warrant exercise price (in dollars per share)		$ 0.99

[1] If the Company subdivides (by any stock split, stock dividend, recapitalization or otherwise) its outstanding shares of its common stock into a smaller number of shares, the warrant exercise price is proportionately reduced and the number of shares under outstanding warrants is proportionately increased. Additionally, if the Company combines (by combination, reverse stock split or otherwise) its outstanding shares of common stock into a smaller number of shares, the warrant exercise price is proportionately increased and the number of shares under outstanding warrants is proportionately decreased.