Collaboration Agreements - Summary of Total Consolidated Revenue from Strategic Collaborators (Details) - Collaboration - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Collaboration Agreements [Line Items]
Total collaboration revenue	$ 28	$ 1,157	$ 25,877	$ 15,238
Jazz
Collaboration Agreements [Line Items]
Total collaboration revenue	$ 28	118	26,044	11,225
Sarepta
Collaboration Agreements [Line Items]
Total collaboration revenue		$ 1,039	$ (167)	$ 4,013