Derecognition of Business - Additional Information (Details) - USD ($)		3 Months Ended	9 Months Ended
	Nov. 15, 2021	Sep. 30, 2022	Sep. 30, 2022
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Impairment of prepaid manufacturing services		$ 4,508,000	$ 4,508,000
Lonza
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Aggregate fair value of non-cash consideration	$ 39,200,000
Prepaid manufacturing services utilized		500,000	500,000
Asset Purchase Agreement | Lonza
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Consideration transactions	$ 65,000,000.0
Manufacturing Services Agreement | Lonza
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Clinical program period	4 years
Agreement termination advance notice period	12 months
Prepaid manufacturing services utilized		$ 500,000	500,000
Impairment of prepaid manufacturing services			4,500,000
License and Collaboration Agreement | Lonza
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Sublicense revenue			$ 0
Sublease Agreement | Lonza
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Lease commencement date	Nov. 15, 2021
Lease expiration date	Nov. 30, 2024
Annual fixed rent charges	$ 1,000,000.0
Percentage of annual increase in fixed rent charges	2.80%