Collaboration Agreements - Summary of Total Consolidated Revenue from Strategic Collaborators (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Collaboration Agreements [Line Items]
Total collaboration revenue	$ 13,145	$ 890	$ 25,849	$ 14,081
Jazz
Collaboration Agreements [Line Items]
Total collaboration revenue	13,312	(511)	26,016	11,107
Sarepta
Collaboration Agreements [Line Items]
Total collaboration revenue	$ (167)	$ 1,401	$ (167)	$ 2,974