Collaboration Agreements - Summary of Total Consolidated Revenue from Strategic Collaborators (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Collaboration Agreements [Line Items]
Total collaboration revenue	$ 12,704	$ 13,191
Jazz
Collaboration Agreements [Line Items]
Total collaboration revenue	$ 12,704	11,618
Sarepta
Collaboration Agreements [Line Items]
Total collaboration revenue		$ 1,573