Accrued Expenses - Schedule of Accrued Expenses (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Payables and Accruals [Abstract]
Accrued employee compensation	$ 3,470	$ 5,142
Accrued external research and development costs	1,852	2,420
Accrued professional services and consulting	988	1,523
Accrued facilities costs	90	190
Other expenditures	408	428
Accrued expenses	$ 6,808	$ 9,703