Income Taxes - Summary of Significant Components of Company's Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Deferred tax assets:
Net operating loss carryforwards	$ 51,672	$ 37,609
Capitalized license and research and development payments	7,786	8,393
Research and development credits	15,062	11,910
Deferred revenue	11,919	17,117
Lease liabilities	10,105	10,519
Accrued bonus	1,085	1,053
Stock compensation	4,344	3,335
Other temporary differences	289	349
Total deferred tax assets	102,262	90,285
Valuation allowance	(93,091)	(80,758)
Deferred tax assets	9,171	9,527
Deferred tax liabilities:
Right-of-use asset	(5,996)	(6,007)
Depreciation	$ (3,175)	$ (3,520)