Income Taxes - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Income Taxes [Line Items]
Income tax benefits for net operating losses	$ 0	$ 0
Changes in valuation allowance for deferred tax assets	12,300,000	27,500,000
Unrecognized tax benefits	$ 0	0
Operating loss carryforwards, limitations on use	Net operating loss carryforwards may become subject to an annual limitation in the event of certain cumulative changes in the ownership interest of significant shareholders over a three-year period in excess of 50%, as defined under Sections 382 and 383 of the Internal Revenue Code, respectively, as well as similar state provisions.
Accrued interest related to uncertain tax positions	$ 0	0
Accrued penalties related to uncertain tax positions	0	0
Interest amounts recognized	0	0
Penalty amounts recognized	0	$ 0
Domestic Tax Authority
Income Taxes [Line Items]
Net operating loss carryforwards	189,400,000
Deferred tax assets, operating loss carryforwards, not subject to expiration	152,900,000
Deferred tax assets, operating loss carryforwards, subject to expiration	36,400,000
Domestic Tax Authority | Research Tax Credit Carryforward
Income Taxes [Line Items]
Tax credit carryforward	$ 10,500,000
Tax credit carryforward, expiration year	2035
State
Income Taxes [Line Items]
Net operating loss carryforwards	$ 188,700,000
Operating loss carryforwards, expiration year	2035
State | Research Tax Credit Carryforward
Income Taxes [Line Items]
Tax credit carryforward	$ 5,000,000.0
Tax credit carryforward, expiration year	2031