Collaboration Agreements - Schedule of Transaction Price Allocated to Identified Performance Obligation (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Jun. 17, 2020
Collaboration and License Agreement | Jazz Pharmaceuticals Ireland Limited
Collaboration Agreements [Line Items]
License and Services Performance Obligation: Initial Collaboration Target #1	$ 12,717
License and Services Performance Obligation: Initial Collaboration Target #2	13,702
License and Services Performance Obligation: Initial Collaboration Target #3	10,866
License and Services Performance Obligation: Initial Collaboration Target #4	13,593
Additional Target or Program Material Right Performance Obligation	2,812
Replacement Target Material Right Performance Obligation	1,188
Backup Candidate Material Right Performance Obligation: Backup Candidate #1	47
Backup Candidate Material Right Performance Obligation: Backup Candidate #2	47
Transaction Price	$ 54,972
Sarepta Research Agreement
Collaboration Agreements [Line Items]
Transaction Price		$ 18,000
Research License and Services Performance Obligation		11,000
Material Right Performance Obligation: Research Target #1		1,400
Material Right Performance Obligation: Research Target #2		1,400
Material Right Performance Obligation: Research Target #3		1,400
Material Right Performance Obligation: Research Target #4		1,400
Material Right Performance Obligation: Research Target #5		$ 1,400