Collaboration Agreements - Summary of Total Consolidated Net Revenue from Strategic Collaborators (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Collaboration Agreements [Line Items]
Total collaboration revenue	$ 22,935	$ 2,915
Jazz
Collaboration Agreements [Line Items]
Total collaboration revenue	11,322	641
Sarepta
Collaboration Agreements [Line Items]
Total collaboration revenue	$ 11,613	$ 2,274