CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Revenue:
Collaboration revenue	$ 22,935,000	$ 2,915,000
Total revenue	22,935,000	2,915,000
Operating expenses:
Research and development	64,855,000	73,981,000
General and administrative	27,629,000	19,852,000
Total operating expenses	92,484,000	93,833,000
Loss from operations	(69,549,000)	(90,918,000)
Other income (expense):
Gain on disposition	33,286,000
Other income	1,780,000	906,000
Interest income	22,000	253,000
Interest expense	(2,696,000)	(1,906,000)
Total other income (expense), net	32,392,000	(747,000)
Net loss	(37,157,000)	(91,665,000)
Cumulative dividends on redeemable convertible preferred stock		(10,831,000)
Net loss attributable to common stockholders	$ (37,157,000)	$ (102,496,000)
Net loss per share attributable to common stockholders, basic and diluted	$ (1.70)	$ (16.18)
Weighted average common shares outstanding, basic and diluted	21,794,546	6,332,841
Comprehensive loss:
Net loss	$ (37,157,000)	$ (91,665,000)
Other comprehensive loss:
Unrealized loss on investments, net of tax of $0		(43,000)
Total other comprehensive loss	(0)	(43,000)
Comprehensive loss	$ (37,157,000)	$ (91,708,000)