X0306 4 2022-06-17 0 0001659352 Codiak BioSciences, Inc. CDAK 0001654055 Bernstein Karen C/O CODIAK BIOSCIENCES, INC. 35 CAMBRIDGEPARK DRIVE, SUITE 500 CAMBRIDGE MA 02140 1 0 0 0 Stock Option (Right to Buy) 2.83 2022-06-17 4 A 0 7500 0.00 A 2032-06-16 Common Stock 7500 7500 I See footnote Restricted Stock Units 2022-06-17 4 A 0 1500 0.00 A Common Stock 1500 1500 I See footnote This option shall vest in full upon the earlier to occur of (i) June 17, 2023 and (ii) the Issuer's next annual meeting of stockholders. Each restricted stock unit represents a contingent right to receive one share of common stock. On June 17, 2022, David Flores and Karen Bernstein Trust Agreement was granted 1,500 restricted stock units, which shall vest in full upon the earlier to occur of (i) June 17, 2023 and (ii) the Issuer's next annual meeting of stockholders. The reporting person is a trustee of David Flores and Karen Bernstein Trust Agreement. /s/ Yalonda Howze, Attorney-in-Fact for Karen Bernstein 2022-06-21