X0306 4 2022-05-02 0 0001659352 Codiak BioSciences, Inc. CDAK 0001621172 Mauro David J C/O CODIAK BIOSCIENCES, INC. 35 CAMBRIDGEPARK DRIVE, SUITE 500 CAMBRIDGE MA 02140 0 1 0 0 Chief Medical Officer Stock Option (Right to Buy) 3.26 2022-05-02 4 A 0 200000 0.00 A 2032-05-01 Common Stock 200000 200000 D Restricted Stock Units 2022-05-02 4 A 0 20000 0.00 A Common Stock 20000 20000 D 25% of this option shall vest and become exercisable on May 2, 2023, with the remainder vesting in 12 equal quarterly installments thereafter. Each restricted stock unit represents a contingent right to receive one share of common stock. On May 2, 2022, the reporting person was granted 20,000 restricted stock units, with one-third vesting on May 2, 2023, and the remainder vesting in two equal yearly installments on each of the one-year anniversaries thereafter. /s/ Yalonda Howze, by Power of Attorney for David J. Mauro 2022-05-04