X0306 4 2019-06-13 0 0001659323 Iterum Therapeutics plc ITRM 0001365617 Heron Patrick J C/O ITERUM THERAPEUTICS PLC, BLK 2 FL. 3, HARCOURT CENTRE, HARCOURT ST. DUBLIN L2 2 IRELAND 1 0 1 0 Stock Option (Right to Buy) 6.74 2019-06-13 4 A 0 9836 0.00 A 2029-06-12 Ordinary Shares 9836 9836 D Restricted Stock Units 2019-06-13 4 A 0 2852 0.00 A Ordinary Shares 2852 2852 D Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Equity Incentive Plan, the shares subject to this option shall vest on June 13, 2020. Each restricted stock unit ("RSU") represents the contingent right to receive one ordinary share upon vesting of the RSU. Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Equity Incentive Plan, the RSUs shall vest on June 13, 2020. /s/ Patrick J. Heron 2019-06-17