X0306 4 2019-06-13 0 0001659323 Iterum Therapeutics plc ITRM 0001245624 HEALY JAMES C/O ITERUM THERAPEUTICS PLC, BLK 2 FL. 3, HARCOURT CENTRE, HARCOURT ST. DUBLIN L2 2 IRELAND 1 0 1 0 Restricted Stock Units 2019-06-13 4 A 0 5703 0.00 D Ordinary Shares 5703 5703 D Each restricted stock unit ("RSU") represents the contingent right to receive one ordinary share upon vesting of the RSU. Subject to the reporting person providing continuous service to the Issuer and the other terms and conditions of the Issuer's 2018 Equity Incentive Plan, the RSUs shall vest on June 13, 2020. /s/James I. Healy 2019-06-17