75000 - Document - Document and Entity Information
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75010 - Statement - CONSOLIDATED BALANCE SHEETS
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75020 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical)
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75030 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS
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75040 - Statement - CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS
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75050 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY
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75060 - Statement - CONSOLIDATED STATEMENTS OF REDEEMABLE CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS' EQUITY (DEFICIT) (Parenthetical)
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75070 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS
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75080 - Disclosure - Cybersecurity Risk Management, Strategy, and Governance
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995455 - Disclosure - Nature of Business
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995465 - Disclosure - Summary of Significant Accounting Policies
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995475 - Disclosure - Product Revenue, Net
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995495 - Disclosure - Inventories
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995505 - Disclosure - Property and Equipment, Net
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995515 - Disclosure - Accrued Expenses
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995525 - Disclosure - Convertible Notes
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995535 - Disclosure - Fair Value Measurements
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995545 - Disclosure - Leases
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995555 - Disclosure - Asset Acquisitions and Collaboration Agreements
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995565 - Disclosure - Redeemable Convertible Preferred Stock
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995575 - Disclosure - Stock Option and Grant Plans
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995585 - Disclosure - Common Stock
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995595 - Disclosure - Income Taxes
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995605 - Disclosure - Employee Benefit Plans
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995615 - Disclosure - Net Loss Per Share
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995625 - Disclosure - Segments
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995635 - Disclosure - Related Party Transactions
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995645 - Disclosure - Commitments and Contingencies
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995655 - Disclosure - Restructuring
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995665 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995675 - Disclosure - Summary of Significant Accounting Policies (Tables)
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995685 - Disclosure - Product Revenue, Net (Tables)
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995705 - Disclosure - Inventories (Tables)
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995715 - Disclosure - Property and Equipment, Net (Tables)
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995725 - Disclosure - Accrued Expenses (Tables)
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995735 - Disclosure - Fair Value Measurements (Tables)
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995745 - Disclosure - Leases (Tables)
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995755 - Disclosure - Redeemable Convertible Preferred Stock (Tables)
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995765 - Disclosure - Stockholders' Equity (Deficit) (Tables)
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995775 - Disclosure - Stock Option and Grant Plans (Tables)
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995785 - Disclosure - Income Taxes (Tables)
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995795 - Disclosure - Net Loss Per Share (Tables)
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995805 - Disclosure - Segments (Tables)
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995815 - Disclosure - Nature of Business - Additional Information (Details)
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995825 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details)
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995835 - Disclosure - Summary of Significant Accounting Policies - Schedule of Useful Lives of Property and Equipment (Details)
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995845 - Disclosure - Product Revenue, Net - Additional Information (Details)
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995885 - Disclosure - Inventories - Summary of Inventories (Details)
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995895 - Disclosure - Inventories - Summary of Inventories (Details) 2
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995905 - Disclosure - Inventories - Additional Information (Details)
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995915 - Disclosure - Property and Equipment, net - Summary of Property and Equipment, Net (Details)
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995925 - Disclosure - Accrued Expenses - Schedule of Accrued Expenses (Details)
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995935 - Disclosure - Convertible Notes - Additional Information (Details)
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995945 - Disclosure - Fair Value Measurements - Schedule of Financial Assets and Liabilities Measured at Fair Value on Recurring Basis (Detail)
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995955 - Disclosure - Leases - Additional Information (Details)
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995965 - Disclosure - Leases - Summary of Condensed Consolidated Balance Sheet of Operating Leases (Details)
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995975 - Disclosure - Leases - Summary of Future Minimum Lease Payments (Detail)
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995985 - Disclosure - Leases - Summary of Future Minimum Lease Payments (Detail) 2
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995995 - Disclosure - Leases - Summary of Future Minimum Lease Payments (Detail) 3
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996005 - Disclosure - Asset Acquisitions and Collaboration Agreements - Additional Information (Details)
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996015 - Disclosure - Redeemable Convertible Preferred Stock - Additional Information (Details)
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996025 - Disclosure - Redeemable Convertible Preferred Stock - Schedule of Redeemable Convertible Preferred Stock (Details)
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996035 - Disclosure - Stockholders' Equity (Deficit) - Additional Information (Details)
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996045 - Disclosure - Stockholders' Equity (Deficit) - Schedule of Common Stock Reserved for Future Issuance (Details)
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996055 - Disclosure - Stock Option and Grant Plans - Additional Information (Details)
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996065 - Disclosure - Stock Option and Grant Plans - Summary of Estimate Fair Value of Stock Option Awards on Grant Date (Details)
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996075 - Disclosure - Stock Option and Grant Plans - Summary of Stock Option Activity (Details)
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996085 - Disclosure - Stock Option and Grant Plans - Summary of Restricted Stock Unit Activity (Details)
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996095 - Disclosure - Stock Option and Grant Plan - Summary of Performance-Based Restricted Stock Unit Activity (Details)
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996105 - Disclosure - Stock Option and Grant Plans - Summary of Stock-Based Compensation Expense (Details)
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996115 - Disclosure - Stock Option and Grant Plans - Summary of Stock-Based Compensation by Type of Award (Details)
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996125 - Disclosure - Stock Option and Grant Plans - Summary of Unrecognized Stock-Based Compensation Expense and Weighted-Average Recognition Period (Details)
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996135 - Disclosure - Common Stock - Additional Information (Details)
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996145 - Disclosure - Income Taxes - Components of Net Loss Before Provision for Income Taxes (Details)
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996155 - Disclosure - Income Taxes - Schedule of (Benefit) Provision For Income Taxes (Details)
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996165 - Disclosure - Income Taxes - Additional Information (Details)
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996175 - Disclosure - Income Taxes - Schedule of Reconciliation of Effective Income Tax Rate to U.S. Statutory Federal Income Tax Rate (Details)
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996185 - Disclosure - Income Taxes - Schedule of Reconciliation of Effective Income Tax Rate to U.S. Statutory Federal Income Tax Rate (Details) 2
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996195 - Disclosure - Income Taxes - Summary of Significant Components of Deferred Tax Assets and Liabilities (Details)
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996205 - Disclosure - Income Taxes - Summary of Valuation Allowance (Details)
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996215 - Disclosure - Income Taxes - Summary of Unrecognized Tax Benefits (Details)
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996225 - Disclosure - Income Taxes - Summary of Cash Paid for Income Taxes Net of Refunds Received by Jurisdiction (Details)
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996235 - Disclosure - Employee Benefit Plans - Additional Information (Details)
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996245 - Disclosure - Net Loss Per Share - Schedule of Antidilutive Shares Excluded from the Calculation of Diluted Net Income (Loss) Per Share (Details)
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996255 - Disclosure - Segments - Additional Information (Details)
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996265 - Disclosure - Segments - Schedule of Segment Revenue and Expenses to Consolidated Net Loss (Income) (Details)
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996275 - Disclosure - Segments - Schedule of Segment Revenue and Expenses to Consolidated Net Loss (Income) (Parenthetical) (Details)
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996285 - Disclosure - Related Party Transactions - Additional Information (Details)
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996295 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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996305 - Disclosure - Restructuring - Additional Information (Details)
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996315 - Disclosure - Subsequent Events - Additional Information (Details)
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Weighted Average Grant Date Fair Value, Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Avexitide [Member]
Avexitide.
Avexitide
Income (Loss) from Continuing Operations before Income Taxes, Foreign
Non - U.S.
Percentage of increase in shares outstanding annually
Percentage of Increase in Shares Outstanding Annually
Percent of increase in shares outstanding annually.
Non Rule 10b51 Arr Modified [Flag]
Non Rule 10b51 Arr Modified.
Non-Rule 10b5-1 Arrangement Modified
Concentration Risk Type [Axis]
Schedule of Nonvested Performance-Based Units Activity [Table Text Block]
Summary of Performance-Based Restricted Stock Unit Activity
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
2021 Notes
Two Thousand Twenty One Notes [Member]
Two thousand twenty one notes.
Rebates and other gross to net adjustments.
Rebates and Other Gross To Net adjustments
Accrued returns, rebates and co-pay assistance
Increase (Decrease) in Accounts Payable, Total
Accounts payable
Increase (Decrease) in Accounts Payable
Plan Name
Plan Name [Axis]
Direct research and development expenses by program:
Research and Development Expense [Abstract]
Equity [Abstract]
Entity Current Reporting Status
Entity Current Reporting Status
Operating expenses:
Operating Expenses [Abstract]
Less :
Level 2
Fair Value, Inputs, Level 2 [Member]
Deferred Tax Assets, Net of Valuation Allowance
Net total deferred tax assets
Performance-Based Restricted Stock Units [Member]
Performance-Based Restricted Stock Units.
Performance-Based Restricted Stock Units
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Common stock authorized
Common stock, shares authorized
Common Stock, Shares Authorized
MASSACHUSETTS
Massachusetts
Investment, Policy [Policy Text Block]
Short-Term Investments
Product and Service [Axis]
Document Fiscal Period Focus
Document Fiscal Period Focus
Debt instrument, description
Debt Instrument, Description
Notes secured and carried interest rate
Debt Instrument, Interest Rate, Stated Percentage
Revenue from Contract with Customer [Abstract]
Entity Shell Company
Entity Shell Company
Preferred Shares Outstanding
Temporary equity, shares outstanding
Beginning Balance, Shares
Ending Balance, Shares
Temporary Equity, Shares Outstanding
Other accrued expenses
Other Accrued Liabilities, Current
Short-term Investments
Short-Term Investments [Member]
Weighted average incremental borrowing rate
Operating Lease Weighted Average Incremental Borrowing Rate
Operating lease weighted average incremental borrowing rate.
Segment Reporting, Policy [Policy Text Block]
Segment Information
Cash and Cash Equivalents, at Carrying Value, Total
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Cash and Cash Equivalent
Summary of Condensed Consolidated Balance Sheet of Operating Leases
Operating Leases Balance Sheet Disclosure [Table Text Block]
Operating leases balance sheet disclosure.
Total inventories
Inventory Current and Noncurrent
Inventory current and noncurrent.
Subsidiary Sale Of Stock [Line Items]
Subsidiary, Sale of Stock [Line Items]
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Number of common stock for sale in underwritten public offering
Common Stock, Shares, Issued, Total
Common stock, shares, issued
Common Stock, Shares, Issued
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]
TEXAS
Texas
Cybersecurity Risk Board of Directors Oversight [Text Block]
Operating lease, description
Lessee, Operating Lease, Description
Asset Class
Asset Class [Domain]
Statement [Table]
Statement [Table]
Number of operating lease agreements
Number of Operating Lease Agreements
Number of operating lease agreements.
Restricted cash
Restricted Cash, Noncurrent
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Right-of-use assets obtained in exchange for new operating lease liabilities
Weighted average grant-date fair value of options granted during the period
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value of stock options granted
Summary of Unrecognized Stock-Based Compensation Expense and Weighted-Average Recognition Period
Summary Of Unrecognized Stock Based Compensation Expense And Weighted Average Recognition Period Table [Text Block]
Summary of unrecognized stock-based compensation expense and weighted-average recognition period.
Proceeds from Debt, Net of Issuance Costs
Proceeds from financings, net of issuance costs
Statement [Line Items]
Statement [Line Items]
Business Combination [Domain]
Entity Filer Category
Entity Filer Category
Conversion of preferred stock into common stock upon initial public offering
Conversion of preferred stock into common stock upon initial public offering
Temporary Equity Conversion of preferred stock into common stock upon initial public offering
Temporary Equity Values Conversion Of Preferred Stock Into Common Stock Upon Initial Public Offering
Temporary equity values conversion of preferred stock into common stock upon initial public offering.
Liabilities and Equity
Total liabilities and stockholders' equity
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Payables and Accruals [Abstract]
Significant Change in Unrecognized Tax Benefits, Nature of Event
Significant change in unrecognized tax benefits
Weighted-Average Exercise Price, Options exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Long-Lived Tangible Asset [Axis]
Severance and employee benefit costs
Severance Costs
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Increases (decreases) recorded to income tax provision
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
Proceeds received in advance
Proceeds from Issuance of Debt
Cash and Cash Equivalents, Fair Value Disclosure
Cash equivalents
Increase (Decrease) in Deposits and other assets
Increase (decrease) in deposits and other assets.
Deposits and other assets
Deferred Tax Assets, Valuation Allowance
Valuation allowance
Valuation allowance at beginning of year
Valuation allowance at end of year
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
U.S. Statutory federal income tax rate
U.S. federal statutory tax rate, Percent
Temporary equity issue price per share
Shares Issued, Price Per Share
Operating loss carryforwards, expiration period.
Operating Loss Carryforwards, Expiration Period
Operating loss carryforwards, expiration period
Subsequent Event [Line Items]
Cybersecurity Risk Management Third Party Engaged [Flag]
Documents Incorporated by Reference [Text Block]
Documents Incorporated by Reference
Cash and cash equivalents maturity date description.
Cash And Cash Equivalents Maturity Date Description
Maturity days for highly liquid investments
Other Noncash Income (Expense)
Other Noncash Income (Expense), Total
Other non-cash items
Aggregate Intrinsic Value, Options unvested
Share Based Compensation Arrangement By Share Based Payment Award Options Unvested Intrinsic Value
Share-based compensation arrangement by share-based payment award options unvested intrinsic value.
Effective Income Tax Rate Reconciliation, Percent
Effective income tax rate
Stock Options
ISOs
Incentive Stock Options [Member]
Incentive stock options.
Interest income
Investment Income, Interest
Interest income
Income Tax Jurisdiction [Axis]
Deferred Tax Assets, Operating Loss Carryforwards, Not Subject to Expiration
Operating loss carryforwards, not subject to expiration
Geographical [Domain]
Payments to Acquire Intangible Assets
Purchases of IPR&D assets, including transaction costs
Finished goods
Inventory, Finished Goods, Gross
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Restricted Cash
Restricted Cash Equivalents
Retirement Plan Tax Status [Domain]
Underlying Asset Class
Underlying Asset Class [Domain]
Schedule of Inventory, Current [Table Text Block]
Summary of Inventories
Additional paid-in capital
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock, Ending Balance
Additional Paid in Capital, Common Stock
Percentage of increase in common stock reserved for issuance
Percentage Of Increase In Common Stock Reserved For Issuance
Percentage of increase in common stock reserved for issuance.
Voting rights
Common Stock Number Of Voting Rights
Common stock number of voting rights.
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Property, Plant and Equipment [Line Items]
Number of Options, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Cybersecurity Risk Management, Strategy, and Governance [Table]
Summary of the Numerator and Denominators Used in Computation of Earnings Per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount [Abstract]
Nontaxable or nondeductible items, Amount
Investment, Name [Axis]
Common Stock Reserved for Future Issuance of Share-based Awards
Share-Based Payment Arrangement [Member]
Dividends declared
Dividends Payable
Net income (loss) per share attributable to common stockholders -basic
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Net loss per share - basic
Retirement Benefits [Text Block]
Employee Benefit Plans
Morningside Ventures Investments Limited
Morningside Ventures Investments Limited [Member]
Morningside ventures investments limited.
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Total
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax
Foreign currency translation gain (loss)
Number of Options, Outstanding
Number of Options, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Total current liabilities
Liabilities, Current
Accounts receivable, net
Accounts receivable, net
Increase (Decrease) in Accounts Receivable
Lessee, Operating Lease, Liability, to be Paid, Year Five
2030
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Exercise Price
Fair value of underlying common stock
US Federal
Income Tax Paid, Federal, after Refund Received
Income Tax Paid, Federal, after Refund Received, Total
Domestic Tax Jurisdiction [Member]
Federal
Increases related to tax positions taken during the current year
Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions
Accounting Standards Update [Axis]
Consolidation Items [Domain]
Restructuring and Related Cost, Number of Positions Eliminated, Period Percent
Percentage of reduction in workforce
Stockholders' equity:
Equity, Attributable to Parent [Abstract]
Entity Small Business
Entity Small Business
Increase (Decrease) in Accrued Liabilities
Increase (Decrease) in Accrued Liabilities, Total
Accrued expenses
2021 Notes in December 2020
Two Thousand Twenty One Notes In December Two Thousand Twenty [Member]
Two thousand twenty one notes in December two thousand twenty.
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Stock Based Compensation
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
Nature of Operations [Text Block]
Nature of Business
Preferred Stock
Preferred Stock [Member]
Subsidiary Or Equity Method Investee Sale Of Stock By Subsidiary Or Equity Investee [Table]
Subsidiary or Equity Method Investee, Sale of Stock, Type [Table]
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Deferred Tax Assets, Operating Loss Carryforwards, Subject to Expiration
Operating loss carryforwards, subject to expiration
Number of Options, Cancelled or forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Rent Payment Obligation Beginning Period After Lease Commencement
Rent payment obligation beginning period after lease commencement.
Rent payment obligation beginning period after lease commencement
Stock price
Sale of Stock, Price Per Share
Aggregate intrinsic value, exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Current Foreign Tax Expense (Benefit)
Non-U.S.
Commitments And Contingencies [Line Items]
Commitments And Contingencies [Line Items]
Commitments and contingencies.
Cost, Depreciation and Amortization
Cost, Depreciation and Amortization, Total
Depreciation and amortization expense
Share-Based Payment Arrangement [Text Block]
Stock Option and Grant Plans
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Defined Contribution Plan [Table]
Leases [Abstract]
Cash paid for income taxes net of refunds received by jurisdiction Table Text Block
Cash paid for income taxes net of refunds received by jurisdiction.
Summary of Cash Paid for Income Taxes Net of Refunds Received by Jurisdiction
Amendment Flag
Amendment Flag
Product and Service [Domain]
Gina M. Mazzariello [Member]
Gina M. Mazzariello.
Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount
U.S. federal statutory tax rate
Inventory Disclosure [Text Block]
Inventories
Earnings Per Share, Policy [Policy Text Block]
Net income (loss) per share
Liabilities and Stockholders' Equity (Deficit)
Liabilities and Equity [Abstract]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash used in operating activities
Operating lease liabilities
Increase (Decrease) in Operating Lease Liability
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Common Stock
Common Stock [Member]
Accounting Standards Update and Change in Accounting Principle [Table]
Cybersecurity Risk Role of Management [Text Block]
Tax Credit Carryforward, Amount
Tax credits
Defined Contribution Plan, Employer Discretionary Contribution Amount
Amount of contribution made by the company
Weighted-Average Exercise Price, Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Accrued interest receivable
Interest Receivable, Current
Lessee, Operating Lease, Liability, to be Paid, Year Three
2028
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less: accumulated depreciation
Less: accumulated depreciation
Schedule Of Available For Sale Securities [Line Items]
Debt Securities, Available-for-Sale [Line Items]
Income Tax Paid, by Individual Jurisdiction [Line Items]
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Special Purpose acquisition Corp
Special Purpose acquisition Corp [Member]
Special purpose acquisition corp.
Entity Address, Address Line One
Entity Address, Address Line One
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Summary of Estimate Fair Value of Stock Option Awards on Grant Date
Follow-on offering.
Follow on Offering [Member]
Follow-on Offering
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Axis]
Denominator:
Earnings Per Share [Abstract]
Income Tax, Policy [Policy Text Block]
Income Taxes
Carrying Value
Redeemable convertible preferred stock
Beginning Balance
Ending Balance
Temporary Equity, Carrying Amount, Attributable to Parent
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
Supplemental disclosure of cash flow information:
Supplemental Cash Flow Information [Abstract]
Accrued benefits and incentive compensation
Accrued benefits and incentive compensation.
Investment Type
Investment Type [Axis]
Operating lease right-of-use assets
Operating Lease, Right-of-Use Asset
Deferred Tax Assets, Gross
Total deferred tax assets
2021 Notes
Two Zero Two One Notes [Member]
Two zero two one notes.
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
Accrued royalities grant agreements
Accrued Royalties
Inventory Disclosure [Abstract]
2017 Notes
Two Zero One Seven Notes [Member]
Two zero one seven notes.
Emerging Growth Company Status Policy.
Emerging Growth Company Status Policy [Policy Text Block]
Emerging Growth Company Status
Document Type
Document Type
Amortization period recognized
Amortization Recognized Period
Amortization recognized period.
Income Taxes Paid, Net
Income Taxes Paid, Net, Total
Total income taxes paid, net of refunds received
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Increase in shares
Stock Issued During Period, Shares, Period Increase (Decrease)
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Entity Central Index Key
Entity Central Index Key
Personnel Related Research And Development
Personnel related research and development.
Personnel-related research and development
Debt Securities, Available-for-Sale [Table Text Block]
Schedule of Marketable Securities Classified as Available-for-sale
Asset Acquisition [Table]
Investments, Debt and Equity Securities [Abstract]
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
In Process Research and Development Purchase Expense
In process research and Ddvelopment purchase expense.
Charge for purchase of IPR&D assets
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net increase (decrease) increase in cash, cash equivalents and restricted cash equivalents
Subsequent Event Type [Domain]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Total excluded common stock equivalents
SWITZERLAND
Switzerland
Common stock, stated par value per share
Common Stock, Par or Stated Value Per Share
Accounting Standards Update [Domain]
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent
Other comprehensive income (loss)
Liabilities
Liabilities [Abstract]
Weighted- Average Remaining Contractual Term (in years), Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Asset acquisition, contingent consideration, liability
Asset Acquisition, Contingent Consideration, Liability
Asset Acquisition, Contingent Consideration, Liability, Total
Amortized Cost Basis
Debt Securities, Available-for-Sale, Amortized Cost
Defined Contribution Plan Disclosure [Line Items]
Components of Deferred Tax Assets and Liabilities [Abstract]
Foreign Tax Jurisdiction, Other [Member]
Other
Debt Securities, Available-for-sale, Total
Fair Value
Debt Securities, Available-for-Sale
Asset Acquisitions And Collaboration Agreements [Text Block]
Asset acquisitions and collaboration agreements.
Asset Acquisitions and Collaboration Agreements
Document Financial Statement Error Correction [Flag]
2025
Operating Leases, Future Minimum Payments, Due in Four Years
2026
Number of Options, Exercised
Number of Options, Exercised
Issuance of common stock upon exercise of stock options, Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Number of Options, Options unvested
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Beginning Balance
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested, Number of Shares
Performance Based Restricted Stock Unit [Member]
Performance based restricted stock unit.
Performance-Based Restricted Stock Unit
Debt Disclosure [Abstract]
Germany
GERMANY
Accrued expenses
Accrued Liabilities, Current
Accrued Liabilities, Current, Total
Cost of Sales
Cost of Sales [Member]
Ownership [Domain]
Current Fiscal Year End Date
Current Fiscal Year End Date
Debt Instrument [Table]
Schedule of Long-Term Debt Instruments [Table]
Maximum Royalty amount payable to each grantor
Maximum Royalty Guarantees Commitments Amount Payable To Each Grantor
Maximum royalty guarantees commitments amount payable to each grantor.
Convertible Notes Payable, Total
Convertible notes payable to related party
Convertible Notes Payable
Series A Redeemable Convertible Preferred Stock
Series A Redeemable Convertible Preferred Share
Series A Redeemable Convertible Preferred Shares [Member]
Series A redeemable convertible preferred share.
Proceeds from Grantors
Funding received from grantors
Entity Address, State or Province
Entity Address, State or Province
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Number of shares, Nonvested
Number of shares, Nonvested
Percentage of net sales of products developed under projects
Royalty Guarantees Commitments Annual Installment Payment Percentage Of Net Sales Of Products Developed Under Project
Royalty guarantees commitments annual installment payment, percentage of net sales of products developed under project.
Conversion of preferred stock into common stock upon initial public offering
Conversion of preferred stock into common stock upon initial public offering
Stock Issued During Period, Value, Conversion of Convertible Securities
Weighted- Average Remaining Contractual Term (in years), Options unvested
Share Based Compensation Arrangement By Share Based Payment Award Options Unvested Weighted Average Remaining Contractual Term
Share-based compensation arrangement by share-based payment award options unvested weighted average remaining contractual term.
Business Combinations and Other Purchase of Business Transactions, Policy [Policy Text Block]
Business Combinations and Asset Acquisitions
Investment, Name [Domain]
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Comprehensive loss
Common stock issued and outstanding
Common Stock Shares Issued And Outstanding
Common stock shares issued and outstanding.
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Unrealized Gain
Research and Development Expense, Policy [Policy Text Block]
Research and Development
Common stock available for issuance
Common Stock, Capital Shares Reserved for Future Issuance
Geographical [Axis]
2024
Operating Leases, Future Minimum Payments, Due in Three Years
2025
Increase (Decrease) in Accrued Interest Receivable, Net
Interest receivable
Business Combination, Transaction Cost, Excluding Separately Recognized Transaction
Transaction costs
Accounts Receivable [Member]
Accounts Receivable
Marketable Securities, Current
Marketable securities
Raw materials
Inventory, Raw Materials, Gross
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount
State and local income taxes, net of federal income tax effect
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Summary of Stock-Based Compensation Expense
Other
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Amount
Number of Options, Exercised
Issuance of common stock upon exercise of stock options
Stock Issued During Period, Value, Stock Options Exercised
Comprehensive Income, Policy [Policy Text Block]
Comprehensive Loss
Accrued Expenses
Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block]
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Summary of Significant Components of Deferred Tax Assets and Liabilities
Other Comprehensive Income (Loss), Net of Tax [Abstract]
Other comprehensive income (loss):
Proceeds from Sale and Maturity of Marketable Securities, Total
Proceeds from Sale and Maturity of Marketable Securities
Proceeds from maturities of marketable securities
Subsequent Event [Member]
Subsequent Event
Non-cumulative Dividends per share entitled to receive
Non Cumulative Dividends Per Share Entitled To Receive
Non-cumulative dividends per share entitled to receive.
Accrued external research and development
Accrued External Research And Development Current
Accrued external research and development.
Marketable Securities, Policy [Policy Text Block]
Marketable Securities
Convertible Notes
Convertible Notes [Text Block]
Convertible notes.
Property, Plant and Equipment [Abstract]
Deferred Tax Assets, Inventory
Inventory
Antidilutive Securities
Antidilutive Securities [Axis]
Grant revenue policy.
Grant Revenue Policy [Policy Text Block]
Grant Revenue
Gain contingency recorded amount.
Gain Contingency Recorded Amount
Gain contingency
Foreign
Income Tax Paid, Foreign, after Refund Received
Income Tax Paid, Foreign, after Refund Received, Total
Purchase Commitment, Excluding Long-Term Commitment [Axis]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
State and Local Jurisdiction [Member]
State
Share-Based Payment Arrangement, Cost by Plan [Table Text Block]
Summary of Stock-Based Compensation by Type of Award
Available-for-Sale Securities
Available-for-Sale Securities [Member]
Accumulated Other Comprehensive Income (Loss)
AOCI Attributable to Parent [Member]
Customer [Domain]
ALS Association and ALS Finding a Cure
A L S Association And A L S Finding Cure [Member]
ALS Association and ALS Finding a Cure.
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions and Methodology [Abstract]
Lessee, Operating Lease, Option to Extend
Description of lease extension
Preferred stock, $0.0001 par value; 10,000,000 shares authorized
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued
Selling, General and Administrative Expense, Total
Selling, general and administrative
Selling, General and Administrative Expense
Notes mature date
Debt Instrument, Maturity Date
Accrued royalties
Royalty payable.
Royalty Payable
Minimum
Minimum [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Granted
Financial Instrument
Financial Instrument [Axis]
Current assets:
Assets, Current [Abstract]
Fair Value, Inputs, Level 3 [Member]
Level 3
Segment Reporting [Abstract]
Schedule of Financial Assets and Liabilities Measured at Fair Value on Recurring Basis
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Current liabilities:
Liabilities, Current [Abstract]
Loss On Future Purchase Commitments
Loss on future purchase commitments.
Accrued loss on future purchase commitments
Restructuring and Related Activities Disclosure [Text Block]
Restructuring
Related Party Transactions [Abstract]
Schedule of Activity and Ending Reserve Balance for GTN Adjustments
Schedule Of Gross To Net Adjustments Reserve [Table Text Block]
Schedule of gross to net adjustments reserve.
Summary of Available-for-sale Securities with Unrealized Losses for Less Than 12 Months
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block]
NOL carryforwards
Operating Loss Carryforwards
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Accounts receivable, net
Accounts Receivable, after Allowance for Credit Loss, Current
Operating lease, renewal term
Lessee, Operating Lease, Renewal Term
Income Tax Paid, by Individual Jurisdiction [Abstract]
Restricted cash equivalents
Restricted Cash and Cash Equivalent
Restricted Cash and Cash Equivalents, Total
Commitments and Contingencies
Commitments and contingencies (Note 16)
Lessee, Leases [Policy Text Block]
Leases
Conversion of preferred stock into common stock upon initial public offering, Shares
Conversion of preferred stock into common stock upon initial public offering, Shares
Temporary Equity Shares Conversion Of Preferred Stock Into Common Stock Upon Initial Public Offering
Temporary equity shares conversion of preferred stock into common stock upon initial public offering.
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Nonvested
Weighted Average Grant Date Fair Value, Nonvested
Work in process
Inventory, Work in Process, Gross
Operating lease liability
Total operating lease liabilities
Operating lease, liabilities
Operating Lease, Liability
Auditor Firm ID
Joshua Cohen [Member]
Joshua Cohen.
Forecast [Member]
Forecast
Commitments And Contingencies [Table]
Commitments And Contingencies [Table]
Commitments and contingencies.
Concentration Risk Benchmark [Axis]
Revenue from Contract with Customer, Product and Service [Extensible Enumeration]
Aggregate royalty amount payable to grantor
Royalty Guarantees, Commitments, Amount
Percentage of annual net sales of products commercialized from project
Royalty Guarantees Commitments Percentage Of Annual Net Sales Of Products Commercialized From Project
Royalty guarantees commitments percentage of annual net sales of products commercialized from project.
Percentage of grant received
Royalty Guarantees Commitments Percentage Of Grant Received Payable To Each Guarantor
Royalty guarantees commitments percentage of grant received payable to each guarantor.
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Changes in valuation allowance, Percent
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted-average shares used to compute basic net loss per share - basic
Weighted-average shares used in computing net loss per share - basic
Scenario [Axis]
2021 Notes in January and February 2021
Two Thousand Twenty One Notes In January And February Two Thousand Twenty One [Member]
Two Thousand Twenty One Notes in January and February Two Thousand Twenty One.
Aggregate Intrinsic Value, Options exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Summary of Reconciliation of Effective Income Tax Rate to U.S. Statutory Federal Income Tax Rate
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Long-Lived Tangible Asset [Domain]
Number of customers.
Number Of Customers
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
Deferred Tax Assets, Net [Abstract]
Asset Acquisition, Consideration Transferred, Transaction Cost
Asset acquisition, direct transaction costs
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Cash
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Stock-based compensation expense
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
Changes in valuation allowance
Beginning Balance
Ending Balance
Equity, Attributable to Parent
Total stockholders' equity
Payments to Acquire Investments, Total
Payments to Acquire Investments
Purchases of investments
Preferred stock par value
Preferred Stock, Par or Stated Value Per Share
Basis of Presentation and Consolidation
Basis of Accounting, Policy [Policy Text Block]
Lessee, Operating Lease, Existence of Option to Extend [true false]
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Other
Accruals and other
Statement of Stockholders' Equity [Abstract]
Series C Preferred Stock
Series C Preferred Stock [Member]
Cash Equivalents [Member]
Cash equivalents
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Leasehold Improvements [Member]
Leasehold Improvements
Entity Address, Address Line Two
Fair Value Measurements
Fair Value Disclosures [Text Block]
Netherlands
NETHERLANDS
Schedule of Accrued Expenses
Schedule of Accrued Liabilities [Table Text Block]
Debt Instrument, Name
Debt Instrument, Name [Domain]
Total accrued expenses
Accrued expenses and other current liabilities
Accrued Liabilities and Other Liabilities
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
Summary of Unrecognized Tax Benefits
Area of lease property
Area of lease property.
Area of lease property
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Segment Reporting, Other Segment Item, Amount
Other segment items
Plan Name
Plan Name [Domain]
Income tax disclosure.
Income Tax Disclosure [Line Items]
Nonemployee Director
Nonemployee Director [Member]
Nonemployee director.
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Receivable [Policy Text Block]
Accounts receivable, net
Entity [Domain]
Percentage of stockholding
Equity Method Investment, Ownership Percentage
Unrecognized tax benefits increase decrease resulting from prior period tax positions
Unrecognized Tax Benefits Increase Decrease Resulting From Prior Period Tax Positions
(Decreases) Increases related to tax positions taken during prior years
Cost of Goods and Services Sold, Total
Cost of sales
Cost of Product and Service Sold
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Text Block]
Restructuring Plan
Restructuring Plan [Member]
Restructuring plan.
Current State and Local Tax Expense (Benefit)
U.S. - State
Rule 10b51 Arr Modified [Flag]
Rule 10b51 Arr Modified.
Rule 10b5-1 Arrangement Modified
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Share-based Payment Arrangement, Expensed and Capitalized, Amount, Total
Compensation to be paid
Share-Based Payment Arrangement, Expensed and Capitalized, Amount
Marketable Securitites
Debt Securities [Member]
Deferred Charges, Policy [Policy Text Block]
Deferred Offering Costs
Restructuring Plan [Axis]
Related and Nonrelated Parties [Axis]
Change in fair value of convertible notes
Convertible Debt, Fair Value Disclosures
Foreign Tax Jurisdiction [Member]
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment, net
Entity Address, City or Town
Entity Address, City or Town
Accrued consulting and other professional fees
Accrued Consulting And Other Professional Fess
Accrued consulting and other professional fess.
Agency bonds.
Agency Bonds [Member]
Agency Bonds
Security Exchange Name
Security Exchange Name
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross
Total property and equipment
Schedule of Redeemable Convertible Preferred Stock
Temporary Equity [Table Text Block]
Intersegment Eliminations [Member]
Intersegment Eliminations [Member]
Convertible Note Derivative Policy.
Convertible Note Derivative Policy [Policy Text Block]
Convertible Note - Derivative
Counterparty Name
Counterparty Name [Axis]
Loss before income taxes
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Income before income taxes
Loss before income taxes
Computer hardware and software
Computer Hardware And Software [Member]
Computer Hardware and Software
Concentration Risk Type [Domain]
Gain Loss On Purchase Commitments
Gain loss on purchase commitments.
Loss on purchase commitments
Effective Income Tax Rate Reconciliation Nondeductible Expense Executive compensation Amount
Effective income tax rate reconciliation nondeductible expense executive compensation amount.
Executive compensation
Antidilutive Securities, Name
Antidilutive Securities, Name [Domain]
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent
Foreign tax effects (aggregate), Percent
Stockholders' Equity Note [Abstract]
Intangibles
Deferred Tax Assets, Goodwill and Intangible Assets
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Ending Balance
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Beginning Balance
Total cash, cash equivalents and restricted cash equivalents:
Statistical Measurement
Statistical Measurement [Domain]
Total current assets
Assets, Current
Stock-based compensation recognized
Share-Based Payment Arrangement, Expense
Total stock-based compensation
Unrecognized tax benefits, related to tax credit carryforwards
Unrecognized tax benefits, related to tax credit carryforwards
Document Period End Date
Document Period End Date
Deposits and other assets
Deposits And Other Assets
Deposits and other assets.
Title of Individual
Title and Position [Axis]
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
ICFR Auditor Attestation Flag
Number of Options, Options exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Sales and marketing costs.
Sales And Marketing Costs Policy [Policy Text Block]
Sales and Marketing Costs
Statement of Financial Position [Abstract]
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units
Restricted Stock Unit
Percentage of royalty obligations on future sales
Percentage of Royalty Obligations on Future Sales
Percentage of royalty obligations on future sales.
Collateral for Letter of Credit Issued
Collateralized Debt Obligations [Member]
Revenue recognition
Revenue [Policy Text Block]
Realized loss
Debt Securities, Available-for-Sale, Realized Loss
Unvested restricted stock units
Redeemable Convertible Preferred Stock
Redeemable Convertible Preferred Stock [Member]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Security, Excluded EPS Calculation [Table]
Customer One.
Customer One [Member]
Customer One
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation [Abstract]
Reconciliation of cash, cash equivalents and restricted cash equivalents:
Class of Stock
Class of Stock [Axis]
Debt securities available-for-sale number of positions in an unrealized loss position
Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions
Deferred Tax Liabilities, Net
Total deferred tax liabilities
Total deferred tax liabilities
Total deferred tax liabilities
Change in fair value of convertible notes
Change In Fair Value Of Convertible Notes
Change in fair value of convertible notes.
Change in fair value of Measurement dates
Change in fair value of convertible notes
Ireland
IRELAND
Current Income Tax Expense (Benefit)
Provision for income taxes
Provision for income taxes
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Total liabilities
Liabilities
Gubra Agreement [Member]
Gubra agreement.
Gubra Agreement
Financial Instruments [Domain]
ASC 842
Accounting Standards Update 2018-11 [Member]
Dividends, Total
Dividends paid
Dividends
Dividends
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Amount
Foreign tax effects (aggregate)
Lessee, Operating Lease, Liability, to be Paid, Year Two
2027
Deferred tax assets capitalized research and development costs.
Deferred tax assets capitalized research and development costs
Capitalized research and development costs
Advertising costs
Advertising Expense
Gross product revenue to net product revenue.
Gross Product Revnue To Net Product Revenue [Table Text Block]
Summary of Gross Product Revenue to Net Product Revenue
ILLINOIS
Illinois
Debt securities available-for-sale in an unrealized loss position for greater than 12 months
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Number of Positions
Weighted Average Number of Shares Outstanding, Diluted
Weighted-average shares used to compute diluted net (loss) income per share
Weighted-average shares used to compute diluted net (loss) income per share
Weighted-average shares used in computing net loss per share - diluted
Entity File Number
Securities Act File Number
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Net unrealized (loss) gain on marketable securities
Cover [Abstract]
Deferred Federal, State and Local, Tax Expense (Benefit) [Abstract]
Fair Value, Net Derivative Asset (Liability) Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Schedule of Changes in Derivative Liabilities and 2021 Notes with Significant Unobservable Inputs (Level 3)
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Number of shares, Forfeited
Number of shares, Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Restricted shares forfeited
Investments
Investments [Domain]
Summary of Valuation Allowance [Table Text Block]
Summary of Valuation Allowance
Series C-2 Redeemable Convertible Preferred Stock
Series C-2 Redeemable Convertible Preferred Shares
Series C2 Redeemable Convertible Preferred Shares [Member]
Series C-2 redeemable convertible preferred shares.
Revenue Benchmark [Member]
Revenue Benchmark
Scenario [Domain]
Treasury Bills
US Treasury Securities [Member]
Shares reserved
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized
Number of operating segments
Number of Operating Segments
Sale of Stock
Sale of Stock [Domain]
Deferred rent
Deferred Rent Credit, Noncurrent
Segment Reporting Disclosure [Text Block]
Segments
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Noncash Item [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Percentage of all royalties and cash proceeds from revenue generating transaction
Royalty Guarantees Commitments Percentage Of All Royalties And Cash Proceeds From Revenue Generating Transaction Associated With Project
Royalty guarantees commitments, percentage of all royalties and cash proceeds from revenue generating transaction associated with project.
2015 Plan
Two Thousand Fifteen Stock Option And Restricted Stock Plan [Member]
Two thousand fifteen stock option and restricted stock plan.
Temporary equity conversion price per share
Preferred stock conversion price per share
Preferred Stock, Convertible, Conversion Price
Temporary equity, liquidation preference
Temporary Equity, Liquidation Preference
Total common stock authorized and reserved for future issuance
Common Stock Authorized And Reserved For Future Issuance
Common stock authorized and reserved for future issuance.
Subsequent Event [Table]
Number of shares granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period
Withholding taxes paid on stock-based awards
Withholding taxes paid on stock-based awards
Withholding taxes paid on stock-based awards.
Deferred Tax Assets, Other
Other
Current Federal, State and Local, Tax Expense (Benefit) [Abstract]
Short-term Debt, Type
Short-Term Debt, Type [Domain]
AMX0035 PSP [Member]
AMX0035 PSP.
AMX0035 - PSP
Operating Lease, Expense
Operating lease expense
Milestone Payment For Development Candidate
Milestone payment for development candidate.
Milestone payment for development candidate
Weighted-Average Exercise Price, Options unvested
Share-based Compensation Arrangement by Share-based Payment Award, Option, Nonvested, Weighted Average Exercise Price, Beginning Balance
Share-based Compensation Arrangement by Share-based Payment Award, Option, Nonvested, Weighted Average Exercise Price, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Option, Nonvested, Weighted Average Exercise Price
Restructuring expenses
Restructuring Charges
Restructuring Charges, Total
Property, Plant and Equipment, Useful Life
Estimated Useful Life
Short-term Debt, Type
Short-Term Debt, Type [Axis]
Recently Adopted Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Summary of Future Minimum Lease Payments
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Conversion of preferred stock into common stock upon initial public offering, Shares
Conversion of preferred stock into common stock upon initial public offering, Shares
Stock Issued During Period, Shares, Conversion of Convertible Securities
Other
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Percent
Ownership [Axis]
Unreserved common stock available for future issuance
Unreserved Common Stock Available For Future Issuance
Unreserved common stock available for future issuance.
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Stock options and restricted stock units vesting period
Income (Loss) from Continuing Operations before Income Taxes, Domestic
U.S.
Depreciation, Total
Depreciation expense
Depreciation
Investment, Type [Extensible Enumeration]
Eiger BioPharmaceuticals, Inc [Member]
Eiger BioPharmaceuticals, Inc.
Eiger BioPharmaceuticals, Inc.
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense
Interest or penalties related to uncertain tax positions
Operating lease, term of contract
Lessee, Operating Lease, Term of Contract
Common stock, shares, outstanding
Beginning Balance, Shares
Ending Balance, Shares
Common Stock, Shares, Outstanding
Restricted Cash Equivalent, Noncurrent
Restricted cash equivalents
Operating lease liabilities, current portion
Operating lease right-of-use liabilities, current
Operating Lease, Liability, Current
Cybersecurity Risk Management Processes Integrated [Flag]
Document Transition Report
Document Transition Report
Deferred offering cost net of equity financing.
Deferred Offering Cost Net Of Equity Financing
Deferred offering cost net of equity financing
Deferred Tax Assets, Net
Net deferred tax assets
Short-term Investments, Total
Short-term investments
Short-Term Investments
Research and Development Expense, Total
Research and development
Research and Development Expense
Asset Impairment Charges, Total
Impairment charges
Asset Impairment Charges
Property and equipment impairment
Leases
Lessee, Operating Leases [Text Block]
Defined Benefit Plan, Tax Status [Extensible Enumeration]
AMX0035 ALS [Member]
AMX0035 ALS.
AMX0035 - ALS
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
Schedule of (Benefit) Provision For Income Taxes
Deferred Tax Assets, Operating Loss Carryforwards, State and Local
State net operating loss carryforwards
Statement of Cash Flows [Abstract]
Justin Klee [Member]
Justin Klee.
Other Comprehensive (Income) Loss, Defined Benefit Plan, Prior Service Cost (Credit), Reclassification Adjustment from AOCI, after Tax
Other comprehensive income (loss)
Current Federal Tax Expense (Benefit)
U.S. - Federal
Stock Issued During Period, Value, New Issues
Issuance of common stock upon financing, net of issuance costs
Summary of Stock Option Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
2022
Operating Leases, Future Minimum Payments Due, Next 12 Months
2023
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent
Stock-based compensation
Equity [Text Block]
Common Stock
Earnings Per Share [Text Block]
Net Loss Per Share
Temporary Equity [Line Items]
Temporary Equity [Line Items]
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Summary of Restricted Stock Unit Activity
Cybersecurity Risk Management Processes Integrated [Text Block]
Net loss
Net loss
Aggregate Intrinsic Value, Outstanding
Aggregate Intrinsic Value, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Inventory write-downs
Inventory Write-down
Inventories
Increase (Decrease) in Inventories, Total
Inventories
Increase (Decrease) in Inventories
James Frates [Member]
James Frates.
Cash dividend declared or paid
Dividends, Preferred Stock, Cash
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Dividend yield
Percentage of non-cumulative dividends entitled to receive
Percentage Of Non Cumulative Dividends Entitled To Receive
Percentage of non-cumulative dividends entitled to receive.
Available-for-sale investments contractual maturity period
Available For Sale Investments Contractual Maturity Period
Available-for-sale investments contractual maturity period.
Purchase commitments
Purchase Obligation
Purchase Obligation, Total
Operating lease, cash payments
Operating Lease, Payments
Assets
Assets [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
Construction in Progress [Member]
Construction In progress
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other current assets
Restructuring and Related Activities [Abstract]
Document Fiscal Year Focus
Document Fiscal Year Focus
Concentration Risk Benchmark [Domain]
Purchase Commitment
Purchase Commitment [Member]
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flows provided by investing activities:
Other programs [Member]
Other programs.
Other programs
Retirement Benefits [Abstract]
Accounts Payable, Current, Total
Accounts payable
Accounts Payable, Current
Total fair value of stock options vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value
Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]
Components of Net Loss Before Provision for Income Taxes
Research and Development Expense [Member]
Research and Development Expenses
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Marketable Securities
Defined Contribution Plan, Employer Matching Contribution, Percent of Match
Employer contribution percentage of employee compensation to employees
Schedule of common stock reserved for future issuance
Schedule Of Common Stock Reserved For Future Issuance Table [Text Block]
Schedule of common stock reserved for future issuance.
Tax Credit Carryforward, Description
Tax credit carryforward, description
Other contract termination costs and impairment charges
Other Contract Termination Costs And Impairment Charges
Other contract termination costs and impairment charges.
Restructuring Cost and Reserve [Line Items]
Fair Value Measurement, Policy [Policy Text Block]
Fair Value Measurements
Convertible Debt, Total
Convertible debt outstanding
Convertible Debt
Temporary Equity Disclosure [Abstract]
Unrecognized Tax Benefits [Roll Forward]
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
CANADA
Canada
Lessee, Operating Lease, Liability, to be Paid, Year One
2026
Other Assets Included In Accounts Payable And Accrued Expenses
Other assets included in accounts payable and accrued expenses.
Other assets included in accounts payable and accrued expenses
Florida
FLORIDA
Net proceeds of sale in underwritten public offering common stock
Sale of Stock, Consideration Received on Transaction
Company received net proceeds
Debt Instrument
Debt Instrument [Axis]
Share-Based Payment Arrangement [Abstract]
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Unrecognized Expense
Assets, Fair Value Disclosure, Total
Assets, Fair Value Disclosure
Assets measured at fair value
Short term investments held
Sale of Stock
Sale of Stock [Axis]
Concentration Risk, Percentage
Customers accounted for more than 10%
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash provided by investing activities
Title of 12(b) Security
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
Deferred Tax Liabilities, Net [Abstract]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Amount
Stock-based compensation
Income Tax Paid, by Individual Jurisdiction [Table]
Weighted-Average Exercise Price, Cancelled or forfeited
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Forfeited
Restricted cash
Restricted Cash [Member]
Restricted cash.
Money market funds
Money Market Funds [Member]
Income tax disclosure.
Income Tax Disclosure [Table]
Related and Nonrelated Parties [Domain]
Operating lease right-of-use assets.
Increase Decrease In Operating Lease Right Of Use Assets
Operating lease right-of-use assets
Income Tax Disclosure [Text Block]
Income Taxes
Preferred Shares Issued
Temporary equity, shares issued
Temporary Equity, Shares Issued
Restructuring Plan [Domain]
Legal Entity [Axis]
Changes in operating assets and liabilities:
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Property, Plant and Equipment [Table Text Block]
Summary of Property and Equipment, Net
Weighted-Average Exercise Price, Outstanding
Weighted-Average Exercise Price, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Redeemable Convertible Preferred Stock
Preferred Stock [Text Block]
2022 Plan
Two Thousand Twenty Two Stock Option And Incentive Plan [Member]
Two thousand twenty two stock option and incentive plan.
Income Tax Disclosure [Abstract]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value, Recurring and Nonrecurring [Table]
Unrecognized Tax Benefits
Unrecognized tax benefit
Balance at beginning of the period
Balance at end of the period
Additional Paid-In Capital
Additional Paid-in Capital [Member]
UNITED KINGDOM
United Kingdom
Measurement Frequency
Measurement Frequency [Domain]
Income Statement Location
Statement of Income Location, Balance [Axis]
Proceeds from underwritten public offering net of underwriting discount and commissions
Proceeds From Underwritten Public Offering
Proceeds from underwritten public offering.
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Trading Symbol
Trading Symbol
Accrued manufacturing.
Accrued Manufacturing
Accrued manufacturing
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment, Net
Schedule Of Related Party Transactions By Related Party [Table]
Related Party Transaction [Table]
Board of Director
Director [Member]
Subsequent Event Type [Axis]
Employee-related Liabilities, Current
Employee-related Liabilities, Current, Total
Accrued employee compensation and benefits
Cash flows provided by financing activities:
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Initial Upfront Payment
Initial upfront payment.
Initial upfront payment
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years)
Fair Value Measurements, Recurring
Fair Value, Recurring [Member]
Entity Ex Transition Period
Entity Ex Transition Period
Total undiscounted lease payments
Lessee, Operating Lease, Liability, to be Paid
Series C-1 Redeemable Convertible Preferred Stock
Series C-1 Redeemable Convertible Preferred Shares
Series C1 Redeemable Convertible Preferred Shares [Member]
Series C-1 redeemable convertible preferred shares.
Less: imputed interest
Less: imputed interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Research and development tax credits, Percent
Research and development tax credits, Percent
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
Equity Components
Equity Components [Axis]
Inventory acquired expensed as research and development expense
Research and Development Expense (Excluding Acquired in Process Cost)
Total direct research and development expenses by program
Total direct research and development expenses by program
2023
Operating Leases, Future Minimum Payments, Due in Two Years
2024
Nonoperating Income (Expense)
Total other income, net
Equity Component
Equity Component [Domain]
Asset Class
Asset Class [Axis]
State and Local Tax Jurisdiction, Other [Member]
Other
Accrued Rebates
Accrued rebates.
Accrued rebates
Document Annual Report
Business Combination [Axis]
Initial Public Offering
IPO [Member]
Customer [Axis]
Options expiration period
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Issuance of common stock upon vesting of RSUs
Issuance Of Common Stock Upon Vesting Of Rsus
Issuance of common stock upon vesting of rsus.
License and Collaboration Agreements
Collaborative Arrangement, Accounting Policy [Policy Text Block]
US Treasury and Government [Member]
Treasury notes
Type of Borrower [Axis]
Statement of Comprehensive Income [Abstract]
Deferred Tax Assets, Operating Loss Carryforwards, Domestic
Federal net operating loss carryforwards
Maximum
Maximum [Member]
Statistical Measurement
Statistical Measurement [Axis]
Weighted-Average Exercise Price, Exercised
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued
Common stock, $0.0001 par value; 300,000,000 shares authorized; 109,884,502 and 68,629,738 shares issued and outstanding as of December 31, 2025 and 2024, respectively
Acquired in-process research and development
Acquired In Process Research And Development
Acquired in process research and development.
Realized gains
Debt Securities, Available-for-Sale, Realized Gain
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Impairment of Long-Lived Assets
Net unrealized gain (loss) on investments held
Other Comprehensive Income (Loss), Available-for-sale Securities Adjustment, Net of Tax, Portion Attributable to Parent, Total
Other Comprehensive Income (Loss), Available-for-Sale Securities Adjustment, Net of Tax, Portion Attributable to Parent
New Accounting Pronouncements Not Yet Adopted
New Accounting Pronouncements Not Yet Adopted Policy Policy [Text Block]
New accounting pronouncements not yet adopted policy.
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
State and local income taxes, net of federal income tax effect, Percent
Other Nonoperating Income (Expense) [Abstract]
Other income, net:
Entity Public Float
Additional Amount Eligible To Receive Upon Achievement Of Certain Milestones
Additional amount eligible to receive upon achievement of certain milestones.
Additional amount eligible to receive upon achievement of certain milestones
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected volatility
Preferred stock shares authorized
Preferred Stock, Shares Authorized
Royalty expense
Royalty Expense
Total operating expenses
Costs and Expenses
Underlying Asset Class
Underlying Asset Class [Axis]
Other Director or Officer [Member]
Other director or officer.
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Revenue from Contract with Customer [Text Block]
Product Revenue, Net
Entity Registrant Name
Entity Registrant Name
Unrealized Loss
Unrealized loss
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Entity Voluntary Filers
Entity Voluntary Filers
Customer Concentration Risk [Member]
Customer Concentration Risk
Payments to Acquire in Process Research and Development
Acquired in-process research and development expense
Other Nonoperating Income (Expense), Total
Other Nonoperating Income (Expense)
Other expense, net
Subsequent Events [Abstract]
Restricted cash equivalents.
Restricted Cash equivalents [Member]
Restricted Cash Equivalents
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
Income Tax Expense (Benefit)
Provision (benefit) for income taxes
(Benefit) provision for income taxes
Provision (benefit) for income taxes
Measurement Frequency
Measurement Frequency [Axis]
Cash paid at closing
Payments to Acquire Productive Assets
Payments to Acquire Productive Assets, Total
Proceeds from Issuance of Common Stock
Net proceeds from offering
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Schedule of Probability Weighted Valuation Model Used to Value Derivative Liability
Impairment of capitalized internal-use software
Capitalized Computer Software, Accumulated Amortization
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentrations of Credit Risk
Compensation Related Costs, Policy [Policy Text Block]
Stock-Based Compensation Expense
Qualified Plan [Member]
Qualified Plan
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated other comprehensive income (loss)
Consolidation Items [Axis]
Commitments and Contingencies, Policy [Policy Text Block]
Contingencies
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Payments to Acquire Property, Plant, and Equipment
Class of Financing Receivable, Type of Borrower [Domain]
Number of shares, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Restricted shares granted
Temporary Equity By Class Of Stock [Table]
Temporary Equity, by Class of Stock [Table]
Total assets
Assets
Inventory, Policy [Policy Text Block]
Inventories
Property, Plant and Equipment [Table]
Income Tax Paid, State and Local, after Refund Received
Income Tax Paid, State and Local, after Refund Received, Total
US state and local
Weighted- Average Remaining Contractual Term (in years), Options exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Alzheimer's Drug Discovery Foundation, the Alzheimer's Association, and Cure Alzheimer's Fund
Alzheimers Drug Discovery Foundation Alzheimers Association And Cure Alzheimers Fund [Member]
Alzheimers Drug Discovery Foundation, Alzheimers Association, and Cure Alzheimers Fund.
Income Statement [Abstract]
Restructuring Cost [Table]
2023 Inducement Plan
Two Thousand And Twenty Three Inducement Plan [Member]
Two thousand and twenty three inducement plan.
Selling, General and Administrative Expenses [Member]
Selling, General and Administrative Expenses
Number of shares sale in underwritten public offering
Number of shares issued and sold
Sale of Stock, Number of Shares Issued in Transaction
Stock Issued During Period, Shares, New Issues
Issuance of common stock upon financing, net of issuance costs, Shares
Preferred Shares Authorized
Temporary equity, shares authorized
Temporary Equity, Shares Authorized
Number of shares, Vested
Number of shares, Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Restricted shares vested
Proceeds From Exercise Of Stock Options And Restricted Stock Units Vesting
Proceeds from exercise of stock options and restricted stock units vesting.
Proceeds from exercise of stock options and RSUs vesting
Net income (loss) per share attributable to common stockholders -diluted
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Net loss per share - diluted
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Schedule of segment revenue and expenses to consolidated net loss (income)
Operating Segments [Member]
Operating Segments [Member]
Title of Individual
Title and Position [Domain]
Purchase Commitment, Excluding Long-Term Commitment [Domain]
Retirement Plan Tax Status [Axis]
Property, Plant, and Equipment, Useful Life, Term, Description [Extensible Enumeration]
City Area Code
City Area Code
Auditor Name
Employee Stock Purchase Plan
Employee Stock Purchase Plan [Member]
Employee stock purchase plan.
Series B Redeemable Convertible Preferred Stock
Series B Redeemable Convertible Preferred Shares
Series B Redeemable Convertible Preferred Shares [Member]
Series B redeemable convertible preferred shares.
Aggregate convertible notes issued
Debt Instrument, Face Amount
Convertible note beneficial conversion feature policy.
Convertible Note Beneficial Conversion Feature Policy [Policy Text Block]
Convertible Note - Beneficial Conversion Feature
Percentage of cash proceeds from revenue generating transaction
Royalty Guarantees Commitments Percentage Of Cash Proceeds From Revenue Generating Transaction Under Project
Royalty guarantees commitments, percentage of cash proceeds from revenue generating transaction under project.
Deferred Tax Assets, Tax Credit Carryforwards, Total
Deferred Tax Assets, Tax Credit Carryforwards
Tax credits
Counterparty Name
Counterparty Name [Domain]
Research and development tax credits
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount
Research and development tax credits
Estimated Useful Life
Property Plant and Equipment Estimated Useful Live
Property plant and equipment estimated useful live.
Weighted-average remaining lease term (years)
Operating Lease, Weighted Average Remaining Lease Term
Segment Reporting Information [Line Items]
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Property and equipment, net
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Property, Plant and Equipment, Net
Total property and equipment, net
2026
Operating Leases, Future Minimum Payments, Due in Five Years
2027
Non-U.S.
Deferred Foreign Income Tax Expense (Benefit)
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Cash, cash equivalents and restricted cash equivalents, beginning of year
Cash, cash equivalents and restricted cash equivalents, end of year
Operating Income (Loss)
(Loss) income from operations
Loss from operations
Accumulated Deficit
Retained Earnings [Member]
Share-based Payment Arrangement, Noncash Expense, Total
Stock-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Asset Acquisition, Consideration Transferred
Asset Acquisition, Consideration Transferred, Total
Total purchase consideration
Issuance costs
Payments of Stock Issuance Costs
Schedule of estimated useful lives of property and equipment.
Schedule of Estimated Useful Lives of Property and Equipment [Table Text Block]
Schedule of Estimated Useful Lives of Property and Equipment
Operating lease liabilities, net of current portion
Operating Lease, Liability, Noncurrent
Level 1
Fair Value, Inputs, Level 1 [Member]
Class Of Stock [Line Items]
Class of Stock [Line Items]
Net cash provided by financing activities
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Notes Payable, Total
Notes including accrued interest
Notes Payable
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent [Abstract]
Nontaxable or nondeductible items, Percent
Asset Acquisition [Abstract]
Auditor Location
Inventory impairment and loss on firm purchase commitments
Cost of sales inventory impairment and loss on firm purchase commitments
Cost of sales inventory impairment and loss on firm purchase commitments.
Cost of sales - inventory impairment and loss on firm purchase commitments
US Government Corporations and Agencies Securities [Member]
U.S. Agency Bonds
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Antidilutive Shares Excluded from the Calculation of Diluted Net (Loss) Income Per Share
Corporate Debt Securities
Corporate Debt Securities [Member]
Income Tax Jurisdiction [Domain]
Debt Securities, Available-for-Sale [Table]
Entity Interactive Data Current
Entity Interactive Data Current
Income Statement Location
Statement of Income Location, Balance [Domain]
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Cash flows used in operating activities:
Underwritten Public Offering [Member]
Underwritten Public Offering.
Underwritten Public Offering
Furniture and Fixtures [Member]
Furniture and Fixtures
Asset Acquisition [Line Items]
Common Stock Issuable Upon Conversion
Additional common stock issued to holders of redeemable convertible preferred stock
Convertible Preferred Stock, Shares Issued upon Conversion
Accretion (Amortization) of Discounts and Premiums, Investments
Accretion of investment discounts, net
Patent Related Costs Policy.
Patent Related Costs Policy [Policy Text Block]
Patent-Related Costs
Raw Material Purchases and Manufacturing Services
Raw Material Purchases And Manufacturing Services [Member]
Raw material purchases and manufacturing services.
Entity Tax Identification Number
Entity Tax Identification Number
Share Price
Grant price
Effect of exchange rate changes on cash, cash equivalents and restricted cash
Effect of exchange rate changes on cash, cash equivalents and restricted cash
Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Effect of exchange rate changes on cash, cash equivalents and restricted cash equivalents
Local Phone Number
Local Phone Number
Collateral for Corporate Credit Card Program
Collateralized Credit Card Securities [Member]
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Total unrecognized compensation expense related to stock options
Auditor Opinion [Text Block]
Royalty Payments Agreements with Grantors
Royalty Agreement Terms [Member]
Executive compensation
Effective Income Tax Rate Reconciliation Nondeductible Expense Executive compensation
Effective income tax rate reconciliation nondeductible expense executive compensation.
Accounting Policies [Abstract]
Debt securities available-for-sale number of positions
Debt securities available for sale number of positions
Debt securities available for sale number of positions.
Product revenue, net
Revenue from Contract with Customer, Excluding Assessed Tax
Product revenue, net
Lessee, Operating Lease, Liability, to be Paid, Year Four
2029
Customer two.
Customer Two [Member]
Customer Two
Class of Stock
Class of Stock [Domain]
Total operating lease liabilities
Operating Leases, Future Minimum Payments Due
Commercial Paper
Commercial Paper [Member]
Commercial paper
Shares available for future issuance
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Weighted-average recognition period
Weighted-average Recognition Period
Schedule Of Stock By Class [Table]
Stock, Class of Stock [Table]
Entity Emerging Growth Company
Entity Emerging Growth Company
CO Chief Executive Officer [Member]
CO chief executive officer.