Commitment and Contingencies - Additional Information (Details)	6 Months Ended	31 Months Ended
	Jun. 30, 2022 USD ($) LeaseAgreement	Feb. 28, 2019 USD ($)	Dec. 31, 2021 USD ($)
Commitments And Contingencies [Line Items]
Number of operating lease agreements | LeaseAgreement	2
Restricted cash	$ 419,000		$ 189,000
Royalty Payments Agreements with Grantors
Commitments And Contingencies [Line Items]
Proceeds from grants		$ 4,300,000
Royalty Payments Agreements with Grantors | ALS Association and ALS Finding a Cure
Commitments And Contingencies [Line Items]
Percentage of grant received		150.00%
Percentage of net sales of products developed under projects		3.00%
Percentage of cash proceeds from revenue generating transaction		3.00%
Royalty Payments Agreements with Grantors | Alzheimer's Drug Discovery Foundation, the Alzheimer's Association, and Cure Alzheimer's Fund
Commitments And Contingencies [Line Items]
Maximum Royalty amount payable to each grantor		$ 15,000,000.0
Aggregate royalty amount payable to grantor		$ 45,000,000.0
Percentage of annual net sales of products commercialized from project		4.00%
Percentage of all royalties and cash proceeds from revenue generating transaction		15.00%
Collateral for Letter of Credit Issued
Commitments And Contingencies [Line Items]
Restricted cash	200,000
Collateral for Corporate Credit Card Program
Commitments And Contingencies [Line Items]
Restricted cash	$ 200,000