X0609 4 2026-06-18 0 0001658247 Crinetics Pharmaceuticals, Inc. CRNX 0001742616 Okey Stephanie false C/O CRINETICS PHARMACEUTICALS, INC. 6055 LUSK BOULEVARD SAN DIEGO CA 92121 1 0 0 0 0 Common Stock 2026-06-18 4 A 0 5925 0 A 12325 D Stock Option (Right to Buy) 35.87 2026-06-18 4 A 0 9730 0 A 2036-06-18 Common Stock 9730 9730 D The transaction reported on this line involves the receipt of restricted stock units, which represent the right to receive shares of the Issuer's Common Stock, with 100% vesting on the earlier of (a) the first anniversary of the grant date or (b) the next occurring annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service on the board of directors of the Issuer through such vesting date. The stock option shall vest and become exercisable on the earlier of (a) the first anniversary of the grant date or (b) the next occurring annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service on the board of directors of the Issuer through such vesting date. /s/ Tobin Schilke, as attorney-in-fact 2026-06-22