X0407 4 2023-06-08 0 0001658247 Crinetics Pharmaceuticals, Inc. CRNX 0001610381 Vivaldi Coelho Rogerio C/O CRINETICS PHARMACEUTICALS, INC. 10222 BARNES CANYON ROAD, BLDG 2 SAN DIEGO CA 92121 1 0 0 0 0 Common Stock 2023-06-08 4 P 0 5000 22.06 A 5000 D The common stock was purchased by the reporting person in open market transactions on the transaction date, with a volume weighted average purchase price of $22.06 per share. The range of actual purchase prices on the transaction date was $22.02 to $22.08 per share. Detailed information on the exact number of shares purchased at each price can be obtained from the issuer upon request. /s/ Marc Wilson, as attorney-in-fact 2023-06-09